Evidence map›Paper›PMID 39582025›Full record

ArticleJournal of medical case reports2024

A successful application of information technologies in the treatment of multiple sclerosis: a case report.

Naylya Djumaeva

Abstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Naylya DjumaevaMicrobiology, Infectious and Parasitic Diseases, The Research Institute of Virology of the National Specialized Scientific and Practical Medical Center for Epidemiology, 7A Yangi Shahar Street, 100194, Tashkent, Uzbekistan. naila.djumaeva@gmail.com.ORCID http://orcid.org/0000-0001-6850-465X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple sclerosis is a chronic disease of the central nervous system characterized by inflammation, neurodegeneration, and failure of the central nervous system's repair mechanisms. The role of infectious agents against the background of genetic predisposition is currently considered a possible pathogenesis factor of this disease. CASE PRESENTATION: We report the case of a 52-year-old white (Russian) female musician with 15-year history of relapsing-remitting multiple sclerosis who had repeatedly received conventional therapy without much benefit. In 2017, she was admitted to the outpatient department of the Institute of Virology, where she was treated with erythromycin and acyclovir (tablet forms), which were not applied in the traditional way but through the "device for transfer of information from the drug to the human body." The received effect led to suppression of the disease activity, a significant reduction in the symptoms of the disease, prevention of further increase in neurological manifestations of the disease, and improvement in the dynamics of the manifestation of the disease according to brain magnetic resonance imaging.

conclusionThe described case report is innovative and presents for the first time the results of a noninvasive approach to the treatment of a patient with multiple sclerosis in whom information about various medications was introduced into different parts of the body, including the brain. The results obtained may indicate a possible role of infectious agents in the genesis of multiple sclerosis. It indicates a potential impact on them by using a "device for transfer of information from the drug to the human body." The study was conducted in accordance with the principles of the Declaration of Helsinki. It was approved by the Institutional Review Board of the Research Institute of Virology of Uzbekistan (no. 12/8-1500, 1/3/2017).

Indexed as

Magnetic Resonance ImagingMultiple Sclerosis, Relapsing-RemittingAcyclovirErythromycinFemaleHumansMiddle AgedMultiple SclerosisTreatment OutcomeAcyclovirErythromycinAcyclovirDevice for remote transfer of information from a drug to the human bodyErythromycinMedicament testingMRIMultiply sclerosis

Identifiers

PMID39582025
PMCPMC11587738

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.