Evidence map›Paper›PMID 39581832›Full record

ArticleJoint Commission journal on quality and patient safety2025

Development of a Calculator to Determine Individualized Opioid Doses for Treatment of Vaso-Occlusive Episodes for Sickle Cell Disease in the Emergency Department.

Patricia L Kavanagh, John J Strouse, Judith A Paice, Stephanie O Ibemere, Paula Tanabe

Abstract read
In one paragraph

Article in Joint Commission journal on quality and patient safety, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Patricia L Kavanagh
John J Strouse
Judith A Paice
Stephanie O Ibemere
Paula Tanabe

Funding

2/2 A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE)U24HL137907 · NHLBI · DUKE UNIVERSITY · PI BARNHART, HUIMAN X · 2018 to 2021
$5.0M
1/2 A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE)UH3HL137856 · NHLBI · DUKE UNIVERSITY · PI TANABE, PAULA · 2019 to 2021
$1.5M
1/2 A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE)UG3HL137856 · NHLBI · DUKE UNIVERSITY · PI TANABE, PAULA · 2018 to 2018
$432k
NHLBI NIH HHS U24 HL137907NHLBI NIH HHS UG3 HL137856NHLBI NIH HHS UH3 HL137856
6 · The paper itself

Abstract

Sickle cell disease (SCD) is a life-limiting multisystem disease primarily affecting individuals of African and Latinx descent. Its most common complication is painful vaso-occlusive episodes (VOEs), which is also the most common reason individuals with SCD seek care in the emergency department (ED). National guidelines recommend the use of standardized approaches to pain management in the ED, preferably using pain management plans tailored to each patient. However, no standard approach to developing these plans exists. This article describes the development of an opioid calculator to help SCD clinicians create individualized plans to better manage acute painful VOE in the ED setting.

Indexed as

Analgesics, OpioidAnemia, Sickle CellEmergency Service, HospitalHumansPainPain ManagementAnalgesics, Opioid

Identifiers

PMID39581832
PMCPMC11700749

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.