Evidence map›Paper›PMID 39581820›Full record

ArticleUltrasound in medicine & biology2025

Effects of Different Gas Cores on the Ambient Pressure Sensitivity of the Subharmonic Response of SonoVue.

Roozbeh H Azami, Mehmet Yapar, Saikat Halder, Flemming Forsberg, John R Eisenbrey, Kausik Sarkar

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasound in medicine & biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Roozbeh H AzamiDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC, USA.
Mehmet YaparDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC, USA.
Saikat HalderDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC, USA.
Flemming ForsbergDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
John R EisenbreyDepartment of Radiology, Thomas Jefferson University, Philadelphia, PA, USA.
Kausik SarkarDepartment of Mechanical and Aerospace Engineering, The George Washington University, Washington, DC, USA. Electronic address: sarkar@gwu.edu.

Funding

Monodisperse Microbubbles for Noninvasive Pressure EstimationR01EB032333 · NIBIB · THOMAS JEFFERSON UNIVERSITY · PI EISENBREY, JOHN, SARKAR, KAUSIK · 2022 to 2025
$2.4M
NIBIB NIH HHS R01 EB032333
6 · The paper itself

Abstract

objectiveSubharmonic Aided Pressure Estimation (SHAPE) is a noninvasive technique for estimating organ-level blood pressure using the strong correlation between the subharmonic signal and ambient pressure. The compressible gas core of microbubbles enables them to generate linear and nonlinear acoustic responses when exposed to ultrasound. Here, the sulfur hexafluoride (SF

methodsExcitations of 25-700 kPa peak negative pressure (PNP) and 3 MHz transmission frequency were used to study in vitro the effects of overpressure changes ranging from 5 to 25 kPa (37-186 mm Hg).

resultsUnlike SonoVue with SF

conclusionThis study may inform future SHAPE technique developments.

Indexed as

Contrast MediaFluorocarbonsMicrobubblesPhospholipidsPressureSulfur HexafluorideGasesUltrasonographycontrast agent BR1Contrast MediaFluorocarbonsGasesperfluorobutanePhospholipidsSulfur HexafluorideAmbient pressure sensitivityLumasonPerfluorobutaneSonoVueSubharmonic aided pressure estimation (SHAPE)Sulfur hexafluorideUltrasound contrast agents

Identifiers

PMID39581820
PMCPMC11970255

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.