Evidence map›Paper›PMID 39581016›Full record

ArticleJournal of psychiatric research2025

The relationship between sleep and circadian patterns with risk for suicide in bipolar disorder varies by subtype.

Jennifer R Goldschmied, Emma Palermo, Anastasia Yocum, Melvin McInnis, Philip Gehrman

Abstract read
In one paragraph

Article in Journal of psychiatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jennifer R GoldschmiedDepartment of Psychiatry, University of Pennsylvania, 3535 Market St., Philadelphia, PA, 19104, USA. Electronic address: jrgolds2@pennmedicine.upenn.edu.
Emma PalermoCenter for Depression, Anxiety, and Stress Research, McLean Hospital, 115 Mill St., Belmont, MA, 02478, USA. Electronic address: ehpalermo@mclean.harvard.edu.
Anastasia YocumDepartment of Psychiatry, University of Michigan, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA. Electronic address: akyocum@med.umich.edu.
Melvin McInnisDepartment of Psychiatry, University of Michigan, 4250 Plymouth Rd, Ann Arbor, MI, 48109, USA. Electronic address: mmcinnis@umich.edu.
Philip GehrmanDepartment of Psychiatry, University of Pennsylvania, 3535 Market St., Philadelphia, PA, 19104, USA; Behavioral Health Service, Cpl. Michael J. Crescenz VA Medical Center, 3900 Woodland Ave., Philadelphia, PA, 19104, USA. Electronic address: philip.gehrman@pennmedicine.upenn.edu.

Funding

Investigating the Role of Slow-wave Activity as a Marker of Impaired Plasticity in Major Depressive DisorderK23MH118580 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GOLDSCHMIED, JENNIFER RACHEL · 2019 to 2022
$732k
NIMH NIH HHS K23 MH118580
6 · The paper itself

Abstract

introductionSleep and circadian disturbances play a crucial role in psychiatric disorders, especially mood disorders such as bipolar disorder. This study investigated the predictive value of self-reported sleep and circadian factors for suicide risk in individuals with bipolar type I and bipolar type II disorder.

methodsData were collected from the Heinz C. Prechter Longitudinal Study of Bipolar Disorder. Suicide risk was evaluated using the Columbia Suicide-Severity Rating Scale, while the sleep and circadian factors were extracted from the Pittsburgh Sleep Quality Index, Hamilton Depression Rating Scale, and Munich Chronotype Questionnaire.

resultsA stepwise selection procedure identified significant predictors for each group. Results showed that suicide risk in individuals with bipolar disorder type I was associated with insomnia, whereas risk in bipolar disorder type II was associated with evening chronotype.

conclusionThese findings indicate that specific sleep and circadian disturbance variables confer unique risk for suicide in the subtypes of bipolar disorder. This highlights the importance of conducting a thorough sleep and circadian assessment in clinical practice and emphasizes the need for clinical trials investigating the impact of sleep and circadian interventions on mitigating suicide risk in individuals with bipolar disorder.

Indexed as

Bipolar DisorderCircadian RhythmSleepSleep Wake DisordersSuicideAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedPsychiatric Status Rating ScalesRisk FactorsSelf ReportSurveys and QuestionnairesBipolarCircadianPreventionRiskSleepSuicide

Identifiers

PMID39581016
PMCPMC11750613

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.