Evidence map›Paper›PMID 39580787›Full record

ArticleJournal of cellular and molecular medicine2024

Identification and analysis of a cell communication prognostic signature for oral squamous cell carcinoma at bulk and single-cell levels.

Xingwei Zhang, Fan Yang, Chen Dong, Baojun Li, Shuo Zhang, Xiaohui Jiao, Dong Chen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Investigating the role of inflammatory bowel disease-associated gene expression in oral cancer using single-cell RNA sequencing.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xingwei ZhangDepartment of Oral and Maxillofacial Surgery, The First Affiliate Hospital of Harbin Medical University, Harbin, China.
Fan YangDepartment of Stomatology, The First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin, China.
Chen DongDepartment of Beauty and Plastic Surgery, Heilongjiang Provincial Hospital, Harbin, China.
Baojun LiDepartment of Head and Neck Surgery, Harbin Medical University Cancer Hospital, Harbin, China.
Shuo ZhangDepartment of Oral and Maxillofacial Surgery, The First Affiliate Hospital of Harbin Medical University, Harbin, China.
Xiaohui JiaoDepartment of Oral and Maxillofacial Surgery, The First Affiliate Hospital of Harbin Medical University, Harbin, China.
Dong ChenDepartment of Oral and Maxillofacial Surgery, The First Affiliate Hospital of Harbin Medical University, Harbin, China.ORCID 0009-0006-1094-754X

Funding

Research Project of the First Affiliated Hospital of Harbin Medical University 2019M22
6 · The paper itself

Abstract

Head and neck squamous cancer (HNSC) is a heterogenous malignant tumour disease with poor prognosis and has become the current major public health concern worldwide. Oral squamous cell carcinoma (OSCC) is the majority of HNSC. It is still in lack of comprehensive tumour immune microenvironment analysis and prognostic model development for OSCC's clinic practice. Single-cell sequencing data analysis was conducted to identify immune cell subtypes and illustrate cell-cell interaction status in OSCC via R package 'Seurat', 'Harmony', 'elldex' and 'CellChat'. Base on the bulk sequencing data, WGCNA analysis was employed to identify the CD8

Indexed as

Cell CommunicationGene Expression Regulation, NeoplasticMouth NeoplasmsSingle-Cell AnalysisTumor MicroenvironmentBiomarkers, TumorCarcinoma, Squamous CellCD8-Positive T-LymphocytesCell Line, TumorGene Expression ProfilingHistocompatibility Antigens Class IHumansImmunotherapyPrognosisBiomarkers, TumorHistocompatibility Antigens Class Iimmune microenvironmentoral squamous cell carcinomaprognostic model

Identifiers

PMID39580787
PMCPMC11586053

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.