Evidence map›Paper›PMID 39580705›Full record

ArticleJournal of cellular and molecular medicine2024

Effect of Propionate on Citrobacter rodentium Infection in Mice by Regulating NleH Expression.

Yingying Li, Wenjie Mei, Qinhan Zhang, Li Li, Qiaorong Ji

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cellular and molecular medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yingying LiDepartment of Pathophysiology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Wenjie MeiXuzhou Medical University, Xuzhou, Jiangsu, China.
Qinhan ZhangXuzhou Medical University, Xuzhou, Jiangsu, China.
Li LiDepartment of Pathophysiology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, China.
Qiaorong JiDepartment of Pathophysiology, School of Basic Medical Sciences, Xuzhou Medical University, Xuzhou, Jiangsu, China.ORCID 0000-0002-8323-2928

Funding

Jiangsu Training Program of Innovation and Entrepreneurship for Undergraduates 202310313021ZJiangsu Training Program of Innovation and Entrepreneurship for Undergraduates 202410313042YProject of Jiangsu Commission of Health Z2023028Starting Foundation for Talents of Xuzhou Medical University D2021027
6 · The paper itself

Abstract

Propionate is one of the main short chain fatty acids in the gut. Previously, we found that propionate significantly down-regulated the expression of NleH. NleH is a virulence effector secreted by Citrobacter rodentium (C. rodentium, C.r.) and is essential for its intestinal colonisation and infection. Therefore, this study intends to explore the effect and mechanism of propionate on C.r. infection by regulating the expression of NleH. Wild-type C.r. and its NleH mutant (C.r.

Indexed as

Citrobacter rodentiumEnterobacteriaceae InfectionsMice, Inbred C57BLPropionatesAnimalsBacterial AdhesionBacterial ProteinsColonDisease Models, AnimalGene Expression Regulation, BacterialMiceVirulenceBacterial ProteinsPropionatesCitrobacter rodentiumNleHpropionate

Identifiers

PMID39580705
PMCPMC11585961

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.