Evidence map›Paper›PMID 39580633›Full record

Trial reportBiomarkers in medicine2024

The predictive value of CK-MB on the curative effect of urokinase combined with LMWH calcium in AMI.

Hongbin Tang, Yong Liu, Yabing Yu, Jun Zhou, Jiaomei Yang

Abstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Biomarkers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hongbin TangDepartment of Cardiology, Wugang People's Hospital, Wugang, Hunan, China.
Yong LiuDepartment of Cardiology, Wugang People's Hospital, Wugang, Hunan, China.
Yabing YuDepartment of Cardiology, Wugang People's Hospital, Wugang, Hunan, China.
Jun ZhouDepartment of Emergency, Wugang People's Hospital, Wugang, Hunan, China.
Jiaomei YangDepartment of Cardiology, Wugang People's Hospital, Wugang, Hunan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study investigates the predictive value of CK-MB in treating acute myocardial infarction (AMI) with urokinase combined with low molecular weight heparin (LMWH) calcium.

methodsAMI patients treated at our hospital from April 2020 to August 2022 were included in this prospective, multi-center cohort study. Patients were randomly assigned to a urokinase group or a combined treatment group (urokinase plus LMWH). CK-MB levels were measured using ELISA, and adverse reactions were recorded. The accuracy of CK-MB as a predictor was evaluated via ROC curve analysis and AUC.

resultsBefore treatment, CK-MB levels were similar in both groups (

conclusionCK-MB is a valuable predictor for evaluating the efficacy of urokinase plus LMWH in AMI treatment, offering advantages in reducing CK-MB levels and improving outcomes.

Indexed as

Creatine Kinase, MB FormHeparin, Low-Molecular-WeightMyocardial InfarctionUrokinase-Type Plasminogen ActivatorAgedCalciumDrug Therapy, CombinationFemaleHumansMaleMiddle AgedPredictive Value of TestsProspective StudiesROC CurveCalciumCreatine Kinase, MB FormHeparin, Low-Molecular-WeightUrokinase-Type Plasminogen Activatoracute myocardial infarctionCK-MBcurative effectlow molecular weight heparin calciumurokinase

Identifiers

PMID39580633
PMCPMC11654802

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.