Evidence map›Paper›PMID 39580511›Full record

ArticleNature communications2024

Hierarchically mimicking outer tooth enamel for restorative mechanical compatibility.

Junfeng Lu, Jingjing Deng, Yan Wei, Xiuyi Yang, Hewei Zhao, Qihan Zhao, Shaojia Liu, Fengshi Li, Yangbei Li, Xuliang Deng and 2 more

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Nacre-Inspired Composite Coatings with Hierarchical Architecture for Durable Surface Protection.Chemistry of materials : a publication of the American Chemical Society · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Junfeng Lu *School of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Jingjing Deng *Department of Geriatric Dentistry, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Laboratory of Biomedical Materials, Peking University School and Hospital of Stomatology, Beijing, China.
Yan Wei *Department of Geriatric Dentistry, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Laboratory of Biomedical Materials, Peking University School and Hospital of Stomatology, Beijing, China.ORCID 0000-0003-3484-8811
Xiuyi Yang *School of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Hewei Zhao *School of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China. zhaohewei@buaa.edu.cn.ORCID 0000-0001-8851-9920
Qihan ZhaoSchool of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Shaojia LiuSchool of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Fengshi LiSchool of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Yangbei LiSchool of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Xuliang DengDepartment of Geriatric Dentistry, NMPA Key Laboratory for Dental Materials, National Engineering Laboratory for Digital and Material Technology of Stomatology, Beijing Laboratory of Biomedical Materials, Peking University School and Hospital of Stomatology, Beijing, China. kqdengxuliang@bjmu.edu.cn.ORCID 0000-0003-1838-6274
Lei JiangSchool of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China. jianglei@mail.ipc.ac.cn.
Lin GuoSchool of Chemistry, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China. guolin@buaa.edu.cn.ORCID 0000-0002-6070-2384

Funding

National Natural Science Foundation of China (National Science Foundation of China) 52073008National Natural Science Foundation of China (National Science Foundation of China) 52102086National Natural Science Foundation of China (National Science Foundation of China) 52250119
6 · The paper itself

Abstract

Tooth enamel, and especially the outer tooth enamel, is a load-resistant shell that benefits mastication but is easily damaged, driving the need for enamel-restorative materials with comparable properties to restore the mastication function and protect the teeth. Synthesizing an enamel analog that mimics the components and hierarchical structure of natural tooth enamel is a promising way to achieve these comparable mechanical properties, but it is still challenging to realize. Herein, we fabricate a hierarchical enamel analog with comparable stiffness, hardness, and viscoelasticity as natural enamel by incorporating three hierarchies of outer tooth enamel based on hierarchical assembly of enamel-like hydroxyapatite hybrid nanowires with polyvinyl alcohol as a matrix. This enamel analog possesses enamel-similar inorganic components and a nanowire-microbundle-macroarray hierarchical structure. It exhibits toughness of 19.80 MPa m

Indexed as

Dental EnamelDurapatiteHardnessPolyvinyl AlcoholBiomimetic MaterialsElasticityHumansMaterials TestingNanowiresViscosityDurapatitePolyvinyl Alcohol

Identifiers

PMID39580511
PMCPMC11585591

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.