ArticleScientific reports2024
Cytoskeletal regulation on polycaprolactone/graphene porous scaffolds for bone tissue engineering.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- IQGAP Family Proteins in Colorectal Cancer: Molecular Mechanisms and Prognostic Implications.Diagnostics (Basel, Switzerland) · 2026Review
- Nanospider-Generated Polyamide 6 Scaffolds Nanostructured with Graphene Oxide for Enhanced Cell Adhesion and Tissue Development.International journal of molecular sciences · 2026Article
- Comprehensive Characterization of Solution-Cast Polycaprolactone/MXene/Gelatin Composite Films for Biomedical Applications.Biopolymers · 2026Article
- The Combination of Graphene and Polycaprolactone Scaffolds Enhancing Bone Mineralization and Hydroxyapatite.European journal of dentistry · 2026Article
- Chorein Regulates Key Osteoblast Genes in UMR-106 Cells.Cell biochemistry and biophysics · 2026Article
- Biowaste-based hydroxyapatite for bone repair: synthesis from Anadara granosa and Achatina fulica: preliminary study.Brazilian oral research · 2026Article
- Optimizing graphene-enhanced polycaprolactone scaffolds for bone tissue engineering.Journal of oral biology and craniofacial researchArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Understanding cellular mechanics requires evaluating the mechanical and chemical cues that regulate the actin cytoskeleton, particularly filopodia and lamellipodia. Therefore, this study aims to investigate the effect of scaffolds properties on cell migration. The results showed that scaffolds toughness, strain, and strength played a key role in promoting cell movement by stimulating the dynamic formation of filopodia and lamellipodia. The test sample containing 3 wt% G significantly enhanced toughness, yield strength, and strain, leading to increase cell motility as well as enhanced development of longer filopodia and larger lamellipodia in MG-63 cells. These results provide valuable insights for optimizing scaffolds to promote bone tissue regeneration.
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