Evidence map›Paper›PMID 39580428›Full record

ArticleBMC cardiovascular disorders2024

The predictive value of pan-immune inflammatory index for early recurrence of atrial fibrillation after cryoablation.

Pengyang Gu, Peng Xu, Yiqun Chen, Jingyu Li, Hanrui Sun, Haixia Xu, Qi Lu

Abstract read
In one paragraph

Article in BMC cardiovascular disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pengyang GuDepartment of Cardiology, Cardiac Arrhythmia Center, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Peng XuThe Sixth People's Hospital of Nantong, Nantong, 226001, China.
Yiqun ChenMedical College of Nantong University, Nantong, 226001, China.
Jingyu LiDepartment of Cardiology, Cardiac Arrhythmia Center, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Hanrui SunDepartment of Cardiology, Cardiac Arrhythmia Center, Affiliated Hospital of Nantong University, Nantong, 226001, China.
Haixia XuDepartment of Cardiology, Cardiac Arrhythmia Center, Affiliated Hospital of Nantong University, Nantong, 226001, China. ntxhx2005@163.com.
Qi LuDepartment of Cardiology, Cardiac Arrhythmia Center, Affiliated Hospital of Nantong University, Nantong, 226001, China. luqint@sina.com.

Funding

Multi-center Clinical Collaborative Research Project of Affiliated Hospital of Nantong University LCYJ-A04Nantong Science and Technology Project Fund MS22021030
6 · The paper itself

Abstract

objectiveThe pan-immune inflammatory (PIV) index holds prognostic value for cardiovascular diseases. This study aimed to investigate the predictive value of the PIV index regarding recurrence of atrial fibrillation (AF) after cryoballoon ablation (CBA).

methodsThe study included 307 patients with AF. Four inflammatory markers, namely, the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), systemic immune inflammation (SII) index, and PIV index, were used as indicators. COX regression analysis was conducted to evaluate the predictive value of AF recurrence after CBA. A receiver operating characteristic (ROC) curve was plotted, and the area under the curve (AUC) was calculated to evaluate the discriminative power of the indicators.

resultThe PIV index [94.9 (168.9,504.9) vs. 143.2 (98.2,210.6), P < 0.01] and SII index [366.3 (256.6,491.9) vs. 569.9 (658.1,438.4), P < 0.01] were significantly higher in the recurrence group. Univariable COX regression analysis showed that these four indices, persistent AF, and left atrial diameter (LAD) were all associated with AF recurrence. In multivariable regression analysis, the PIV index, persistent AF, and LAD (all P < 0.05) were independent predictors of postoperative AF recurrence. The ROC curve analysis showed that the PIV index had a higher predictive value for AF recurrence (AUC = 0.768, P < 0.01, 95% CI: 0.696-0.840) than the SII index and NLR. Kaplan-Meier analysis showed that patients with a PIV index > 260.7 had a higher recurrence rate at 1-year follow-up (P < 0.01). Subgroup analysis indicated that PIV had a predictive value in patients with different types of AF.

conclusionPIV index may be a potential biomarker for predicting relapse in patients with AF after CBA.

Indexed as

Atrial FibrillationCryosurgeryLymphocytesNeutrophilsPredictive Value of TestsRecurrenceAgedBiomarkersBlood PlateletsFemaleHumansInflammationInflammation MediatorsLymphocyte CountMaleMiddle AgedBiomarkersInflammation MediatorsAtrial fibrillationCryoballoon ablationPan-immune inflammatory indexSystemic immune index

Identifiers

PMID39580428
PMCPMC11585142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.