Evidence map›Paper›PMID 39580405›Full record

SynthesisBMC pulmonary medicine2024

Electrical impedance tomography guided positive end-expiratory pressure titration in critically ill and surgical adult patients: a systematic review and meta-analysis.

Yelin Gao, Huaiwu He, Yi Chi, Inéz Frerichs, Yun Long, Zhanqi Zhao

2 registry-linked trialsAbstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07289113 narecruitingnot on this mapstarted 2026, after this paper: background citation

Personalized PEEP Titration Guided by Electrical Impedance Tomography in Patients Undergoing Laparoscopic Surgery: A Randomized Controlled Trial - The PEaRL Study

TypeinterventionalSponsorASST Fatebenefratelli SaccoRan2026 to 2026Enrolled52ConditionsElectrical Impedance TomographyArmsA PEEP trial performed with the PulmoVista® 500 (Dräger, Lübeck, Germany) is a procedure designed to identify the optimal level of positive end-expiratory pressure
NCT07313644 narecruitingnot on this mapstarted 2025, after this paper: background citation

Electrical Impedance Tomography-Guided Positive End-Expiratory Pressure Optimization in Patients With Trauma-Related and Postoperative Acute Respiratory Distress Syndrome

TypeinterventionalSponsorNguyen Dang ThuRan2025 to 2026Enrolled80ConditionsAcute Respiratory Syndrome Distress, Positive End-Expiratory Pressure, Electrical Impedance Tomography, Trauma and Postoperative Pulmonary InsufficiencyArmsEIT-giuded PEEP, Control
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Observational
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yelin GaoState Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Huaiwu HeState Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. tjmuhhw@126.com.
Yi ChiState Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China.
Inéz FrerichsDepartment of Anesthesiology and Intensive Care Medicine, University Medical Center of Schleswig-Holstein Campus Kiel, Kiel, Germany.
Yun LongState Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. icu_longyun@126.com.
Zhanqi ZhaoState Key Laboratory of Complex Severe and Rare Diseases, Department of Critical Care Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing, China. zhanqi.zhao@gzhmu.edu.cn.

Funding

Beijing Municipal Science and Technology Commission No. Z201100005520051CAMS Innovation Fund for Medical Sciences from Chinese Academy of Medical Sciences 2021-I2M-1-062National High-Level Hospital Clinical Research Funding 2022-PUMCH-D-005National key research and development program 2022YFC2404805National Outstanding Youth Science Fund Project of National Natural Science Foundation of China 82272249
6 · The paper itself

Abstract

objectiveElectrical impedance tomography (EIT) has been used to titrate positive end-expiratory pressure (PEEP). This study aims to develop a comprehensive view of the efficacy and long-term prognosis of EIT-guided PEEP compared to other conventional approaches in various clinical scenarios, including patients with acute respiratory distress syndrome (ARDS), hypoxemic acute respiratory failure (hARF) and patients undergoing surgery under general anesthesia.

methodsThe literature search was conducted in PubMed, Web of Science, Embase, and Cochrane Library, from inception to July 30, 2023 (ARDS/hARF) and October 5, 2023 (surgery). The Cochrane risk of bias assessment and the methodological index for non-randomized studies were used for quality appraisal. The main outcomes were PEEP level, PaO

resultsFour randomized controlled trials (RCTs), one historical control study, and six before-after studies of ARDS/hARF, as well as eight surgical RCTs, were retrieved. Subgroup analysis has been carried out and analysis of before-after studies was performed separately. Diverse PEEP strategies were adopted in the included studies, such as low/high PEEP-FiO

conclusionThe EIT-derived PEEP setting strategy might be associated with potential benefits in respiratory outcomes and prognosis in ARDS/hARF and surgical patients. Current data is insufficient to provide solid evidence.

Indexed as

Critical IllnessElectric ImpedancePositive-Pressure RespirationRespiratory Distress SyndromeTomographyAdultAnesthesia, GeneralHospital MortalityHumansPostoperative ComplicationsRespiratory InsufficiencyAcute respiratory distress syndromeElectrical impedance tomographyGeneral anesthesiaHypoxemic acute respiratory failurePositive end-expiratory pressureSurgerySystematic review, meta-analysis

Identifiers

PMID39580405
PMCPMC11585246

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.