Evidence map›Paper›PMID 39579764›Full record

ArticleCell2025

snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification.

Bei Liu, Tong Wu, Bernadette A Miao, Fei Ji, Shun Liu, Pingluan Wang, Yutao Zhao, Yuhao Zhong, Arunkumar Sundaram, Tie-Bo Zeng and 4 more

Abstract read
In one paragraph

Article in Cell, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. RNA regulation in plants.Science China. Life sciences · 2026
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Cytokine storm.Nature reviews. Disease primers · 2026
    Review
  19. DDIT3 drives nucleus pulposus cell PANoptosis and intervertebral disc degeneration progression.Apoptosis : an international journal on programmed cell death · 2026
    Article
  20. Synthetic short RNA in cancer.Frontiers in oncology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Bei LiuDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Tong WuDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Bernadette A MiaoHoward Hughes Medical Institute, Chicago, IL 60637, USA; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL 60637, USA; Medical Scientist Training Program, The University of Chicago, Chicago, IL 60637, USA.
Fei JiHoward Hughes Medical Institute, Chicago, IL 60637, USA; Department of Radiation and Cellular Oncology, The University of Chicago, Chicago, IL 60637, USA; Ludwig Center for Metastasis Research, The University of Chicago, Chicago, IL 60637, USA.
Shun LiuDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Pingluan WangDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Yutao ZhaoDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Yuhao ZhongDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Arunkumar SundaramDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.
Tie-Bo ZengDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA.
Marta Majcherska-AgrawalHoward Hughes Medical Institute, Chicago, IL 60637, USA; Committee on Genetics, Genomics & System Biology, The University of Chicago, Chicago, IL 60637, USA.
Robert J KeenanDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA.
Tao PanDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA. Electronic address: taopan@uchicago.edu.
Chuan HeDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA; Howard Hughes Medical Institute, Chicago, IL 60637, USA; Department of Biochemistry and Molecular Biology, The University of Chicago, Chicago, IL 60637, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA. Electronic address: chuanhe@uchicago.edu.

Funding

Transcriptome-wide base-resolution sequencing of pseudouridine in human normal and AD brain tissues-CEGS Admin supplement 2020-2021RM1HG008935 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN · 2016 to 2025
$24.4M
Medical Scientist National Research Service AwardT32GM150375 · NIGMS · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2023 to 2026
$5.5M
Membrane protein biogenesis at the ERR35GM145374 · NIGMS · UNIVERSITY OF CHICAGO · PI Robert J Keenan · 2022 to 2026
$3.5M
Targets and functions of the mammalian snoRNAomeR01HG012780 · NHGRI · UNIVERSITY OF CHICAGO · PI HE, CHUAN, PAN, TAO · 2022 to 2025
$2.8M
NHGRI NIH HHS R01 HG012780NHGRI NIH HHS RM1 HG008935NIGMS NIH HHS R35 GM145374NIGMS NIH HHS T32 GM150375
6 · The paper itself

Abstract

Small nucleolar RNAs (snoRNAs) are non-coding RNAs known for guiding RNA modifications, including 2'-O-methylation (N

Indexed as

RNA, Small NucleolarTranscriptomeAnimalsBrainHumansMiceRNA, MessengerSignal Recognition ParticleRNA, MessengerRNA, Small NucleolarSignal Recognition Particleprotein secretionprotein translocationRNA modifications Ψ and N(m)snoRNA-7SL RNA interactionsnoRNA molecular gluesnoRNA-mRNA interaction

Identifiers

PMID39579764
PMCPMC11761385

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.