Observational studyThe Journal of international medical research2024
Association between admission hyperglycaemia with in-hospital mortality rate in patients with hypertension and acute aortic dissection.
Observational study in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Predictive value of preoperative neutrophil-to-lymphocyte ratio for prognosis in aortic dissection patients without hypertension following TEVAR.Frontiers in aging · 2026Article
- Article
- Association between atherogenic index of plasma and ICU 28-day mortality in geriatric diabetes: an EICU-based retrospective analysis.Lipids in health and disease · 2025Article
- Triglyceride-glucose index and risk of abdominal aortic aneurysm: a large-scale prospective cohort study.Diabetology & metabolic syndrome · 2025Article
- Association between triglyceride glucose-body mass index and acute kidney injury and renal replacement therapy in critically ill patients with sepsis: analysis of the MIMIC-IV database.Frontiers in endocrinology · 2025Article
- Association between red blood cell distribution width-to-albumin ratio and all-cause mortality in intracerebral hemorrhage.Frontiers in nutrition · 2025Article
- The systemic inflammation response index as a significant predictor of short-term adverse outcomes in acute decompensated heart failure patients: a cohort study from Southern China.Frontiers in endocrinology · 2024Article
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10 authors.
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Abstract
objectiveAdmission hyperglycaemia is recognized as a contributor to poor outcomes in patients with cardiovascular and cerebrovascular diseases. This study aimed to evaluate the association between admission hyperglycaemia and in-hospital mortality in patients with hypertension and acute aortic dissection (AAD).
methodsPatients diagnosed with hypertension and AAD between 1 January 2010 and 1 March 2023 were enrolled into this retrospective observational study, and divided into two groups based on admission blood glucose levels (BGA): normoglycemia (BGA < 7.8 mmol/L) and hyperglycaemia (BGA ≥ 7.8 mmol/L). The outcome was all-cause in-hospital mortality, which was analysed using logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (CIs).
resultsIn total, 1239 patients were included (comprising 954 [77%] male patients; mean age, 53.0 years; and median BGA, 6.1 mmol/L). Logistic regression analysis showed that in-hospital mortality was 2.53 times greater for patients with hyperglycaemia versus the normoglycaemia group (95% CI 1.68, 3.80). This significant association persisted after adjustments for potential confounders (adjusted OR 2.45 [95% CI 1.58, 3.85]). Restricted cubic spline analysis revealed that the relationship between BGA and mortality reached statistical significance at BGA > 6.1 mmol/L. Stratified analysis and sensitivity analysis confirmed the robustness of this relationship.
conclusionAdmission hyperglycaemia correlated with an elevated risk of in-hospital mortality in patients with hypertension and AAD, particularly BGA > 6.1 mmol/L, indicating that BGA level may be useful in identifying patients who are at an elevated risk of all-cause mortality.
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