Evidence map›Paper›PMID 39579293›Full record

ArticleCardiology and therapy2025

ROsulord® sAfety for Patients with Dyslipidemia Study: A Non-interventional, Multicenter, Prospective, Observational Study in South Korea.

Do Young Kim, Sung Hea Kim, Eung-Ju Kim, Sang-Jin Han, Ji-Yeong Park, Jong-Chan Youn, Hee-Seok Kim, Ji-Eun Jeong, Kyu-Hyung Ryu

Abstract read
In one paragraph

Article in Cardiology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Do Young Kim *Department of Cardiology, Ajou University Hospital, Suwon, Gyeonggi-do, Republic of Korea.
Sung Hea Kim *Department of Cardiology, Konkuk University School of Medicine, Seoul, Republic of Korea.
Eung-Ju KimDepartment of Cardiology, Korea University Guro Hospital, Seoul, Republic of Korea.
Sang-Jin HanDepartment of Cardiology, Hallym University Sacred Heart Hospital, Anyang, Gyeonggi-do, Republic of Korea.
Ji-Yeong ParkDepartment of Cardiology, Nowon Eulji Medical Center, Eulji University, Seoul, Republic of Korea.
Jong-Chan YounDivision of Cardiology, Department of Internal Medicine, Seoul St. Mary's Hospital, Seoul, Republic of Korea.
Hee-Seok KimCatholic Research Institute for Intractable Cardiovascular Disease, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
Ji-Eun JeongChong Kun Dang Pharmaceutical Corporation, Seoul, Republic of Korea.
Kyu-Hyung RyuDepartment of Cardiology, Hebron Medical Center, #102, St.68K, Phum Prey Sala, Sangkat Kakab2, Khan Pou Senchey, Phnom Penh, Cambodia. khryumd@hanmail.net.ORCID http://orcid.org/0000-0001-9329-2716

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe ROsulord® sAfety for patients with Dyslipidemia study (ROAD study) in the Republic of Korea investigated the safety and efficacy of rosuvastatin in routine clinical practice.

methodsThis non-interventional, multicenter, prospective, observational study was conducted over a period of approximately 4.6 years and involved 14,243 participants. During this study, we assessed the adverse events, changes in laboratory test results, and efficacy endpoints associated with rosuvastatin use.

resultsThe findings revealed a notably low adverse event rate of 1.63%, indicating a favorable safety profile for rosuvastatin in the management of dyslipidemia. Importantly, no clinically significant incidences of statin-associated myopathy, hepatotoxicity, or diabetes were observed during the study period. Moreover, this study demonstrated significant improvements in lipid profiles among patients receiving rosuvastatin treatment, with a reduction in total cholesterol, low-density lipoprotein cholesterol, and triglyceride levels. These improvements contributed to a lower cardiovascular risk in the study population.

conclusionOverall, these findings suggest that rosuvastatin is safe and effective in managing dyslipidemia in real-world clinical settings, providing clinicians with valuable insights into the benefits and risks associated with statin therapy in this patient population.

Indexed as

Cardiovascular diseaseDyslipidemiaLipidsMyopathyRosuvastatin

Identifiers

PMID39579293
PMCPMC11893939

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.