Evidence map›Paper›PMID 39579200›Full record

SynthesisJournal of robotic surgery2024

Comparative perioperative outcomes of intravenous indocyanine green during robot-assisted cystectomy: a meta-analysis and systematic review.

Gen Fan, Yinyu Wu, Junji Wang, Yu Wang, Yushui Chen, Ke Hu, Tielong Tang

Abstract readSystematic ReviewMeta-AnalysisComparative Study
PubMed Publisher
In one paragraph

Synthesis in Journal of robotic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Gen FanDepartment of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong, 63700, Sichuan, China.
Yinyu WuDepartment of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong, 63700, Sichuan, China.
Junji WangJintang First People's Hospital/West China Hospital Sichuan University Jintang Hospital, Chengdu, 610000, Sichuan, China.
Yu WangDepartment of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong, 63700, Sichuan, China.
Yushui ChenDepartment of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong, 63700, Sichuan, China.
Ke HuDepartment of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong, 63700, Sichuan, China.
Tielong TangDepartment of Urology/School of Clinical Medicine, North Sichuan Medical College/Affiliated Hospital of North Sichuan Medical College, No. 1, South Maoyuan Road, Shunqing District, Nanchong, 63700, Sichuan, China. cdzt2004@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the clinical utility of intravenous indocyanine green (ICG) in the context of robot-assisted cystectomy (RAC) through a systematic review and meta-analysis. The primary focus was to compare postoperative complications and perioperative outcomes between the ICG cohort and the non-ICG cohort. The primary outcome indicators were the incidence of ureteroenteric strictures and the number of strictures anastomoses. A comprehensive search was performed across multiple databases, including PubMed, Embase, the Cochrane Library, and Web of Science, to identify pertinent studies that evaluate the application of ICG in RAC. The analysis of dichotomous variables was performed using relative risk (RR), while weighted mean difference (WMD) was utilized for comprehensive assessment of continuous variables. A total of 4 studies encompassing 732 patients were included in the analysis, comprising 311 patients who received ICG and 421 patients who did not. The baseline characteristics were found to be comparable between the two cohorts. The meta-analysis indicated that the occurrence of 90-day severe complications was markedly lower in the ICG cohort versus the non-ICG cohort (RR = 0.63, 95% CI 0.44-0.90, P = 0.011). In addition, the length of ureteral resection was longer in the ICG cohort compared to the non-ICG cohort (WMD = 0.25, 95% CI 0.01-0.49, P = 0.039), with notably significant results for right-side procedures (WMD = 0.54, 95% CI 0.28-0.80, P < 0.001). Nevertheless, no substantial differences observed between the two cohorts regarding the occurrence of ureteroenteric stricture, numbers of strictures at anastomoses, operative time (OT), length of hospitalization (LOS), or lymph node positivity. Compared with the non-ICG cohort, the ICG cohort had comparable efficacy and was able to reduce the incidence of 90-day severe complications. The use of intravenous ICG showed promising clinical applicability during RAC; however, additional long-term studies are necessary to substantiate its effectiveness.

Indexed as

CystectomyIndocyanine GreenRobotic Surgical ProceduresAdministration, IntravenousColoring AgentsConstriction, PathologicHumansPostoperative ComplicationsTreatment OutcomeColoring AgentsIndocyanine GreenComplicationsCystectomyIndocyanine greenRobotic surgeryUreteroenteric stricture

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.