Evidence map›Paper›PMID 39578956›Full record

ArticleJournal of cachexia, sarcopenia and muscle2025

Skeletal Muscle

Denisa Kyselova, Irena Mikova, Petr Sedivy, Monika Dezortova, Milan Hajek, Jan Mares, Marek Tupy, Dana Kautznerova, Marek Kysela, Jiri Fronek and 2 more

Abstract read
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Denisa KyselovaDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.ORCID 0000-0001-6652-653X
Irena MikovaDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Petr SedivyDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Monika DezortovaDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Milan HajekDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Jan MaresDepartment of Data Science, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Marek TupyDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Dana KautznerovaDepartment of Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Marek KyselaDepartment of Transplantation Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Jiri FronekDepartment of Transplantation Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Julius SpicakDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Pavel TruneckaDepartment of Hepatogastroenterology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

Funding

Ministry of Health of the Czech Republic IKEM, IN 00023001
6 · The paper itself

Abstract

backgroundSkeletal muscle alterations are associated with higher mortality and morbidity in patients with liver cirrhosis. Assessing these changes seems to be a promising method for identifying patients at a high risk of poor outcomes following liver transplantation (LT). This is particularly important given the current global shortage of organ donors. However, evidence of the impact of these alterations on the prognosis of patients undergoing LT is inconclusive. The aim of our prospective study was to evaluate the impact of skeletal muscle changes, reflected in sarcopenia, myosteatosis and metabolic changes in the calf muscles, on perioperative outcomes and long-term survival after LT. We also sought to determine the posttransplant evolution of the resting muscle metabolism.

methodsWe examined 134 adult LT candidates. Of these, 105 underwent LT. Sarcopenia and myosteatosis were diagnosed by measuring the skeletal muscle index and mean psoas muscle radiation attenuation, respectively, which were obtained from computed tomography (CT) scans taken during pretransplant assessment. Additionally, patients underwent

resultsPatients with abnormal

conclusionsAbnormal

Indexed as

Liver TransplantationMagnetic Resonance SpectroscopyMuscle, SkeletalTomography, X-Ray ComputedAdultAgedFemaleHumansMaleMiddle AgedPrognosisProspective StudiesSarcopenia31P MR spectroscopyliver transplantationmyosteatosissarcopeniaskeletal muscle

Identifiers

PMID39578956
PMCPMC11670159

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.