Evidence map›Paper›PMID 39578899›Full record

SynthesisJournal of medical case reports2024

Myocarditis and pericarditis in young patients following Campylobacter jejuni enterocolitis infection: a systematic review of case studies.

Katharine Sanicola, Nikita Shadani, Eric C Nemec, Suzanne J Rose

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Biomolecules & biomedicine · 2026
    Pooled it
  2. Sequential infections ofAnnals of medicine and surgery (2012) · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katharine Sanicola *Masters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA.
Nikita Shadani *Masters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA.
Eric C NemecMasters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA.
Suzanne J RoseMasters of Science in Physician Assistant Studies, Sacred Heart University, 551 Park Avenue, Fairfield, CT, 06825, USA. srose@stamhealth.org.ORCID http://orcid.org/0000-0001-5770-826X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCampylobacter is known to be the leading cause of foodborne illness. Campylobacter jejuni, specifically, most commonly causes self-limiting enterocolitis, but infection can lead to extraintestinal manifestations, including rare yet severe cardiac complications, such as myocarditis and/or pericarditis. This review aims to determine whether a relationship exists between the timing of a positive stool culture and the overall clinical course in patients with Campylobacter jejuni-associated myocarditis and/or pericarditis.

methodsA systematic search was conducted using PubMed, MEDLINE, CINAHL Ultimate, Academic Search Premier, and Nursing and Allied Health Premium databases. A gray literature search was also performed. Covidence.org was used to screen, select, and extract data by two independent reviewers. Following a full-text evaluation, the quality of each study was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Case Reports.

resultsThe search resulted in 434 records, of which 7 case reports met the inclusion criteria, each study including one patient. The average number of days from hospital presentation to obtaining a stool sample was 1.7. The average number of days from stool culture obtainment to clinical course improvement was 3.3, with four case studies reporting a range of 2-4 days.

conclusionThis systematic review raises awareness regarding the manifestations of Campylobacter jejuni, specifically the severe cardiac symptoms that may present in young individuals. Given the significant sequelae that can develop, providers must elicit a thorough history consisting of questions related to recent travel, food consumption, and gastrointestinal symptoms, especially among young individuals presenting with cardiac complaints.

Indexed as

Campylobacter InfectionsCampylobacter jejuniEnterocolitisMyocarditisPericarditisAnti-Bacterial AgentsCase Reports as TopicHumansAnti-Bacterial AgentsCampylobacter jejuniCardiomyopathyEnterocolitisMyocarditisMyopericarditisPericarditisPerimyocarditis

Identifiers

PMID39578899
PMCPMC11585146

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.