SynthesisBMC psychology2024
A assessment of the effects of parental age on the development of autism in children: a systematic review and a meta-analysis.
Synthesis in BMC psychology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Prenatal Exposure to Ambient Particulate Matter and Autism Spectrum Disorder in Children, a Case Control Study in France.Journal of autism and developmental disorders · 2026Observational
- Sterol pathway disruption in pregnancy: a link to autism.Molecular psychiatry · 2026Article
- The impact of pregestational stress on neurodevelopment: Implications for autism spectrum disorder and attention-deficit/hyperactivity disorder.The Journal of physiology · 2026Review
- Sleep and Behaviour in Early Autism: Examining Bidirectional Associations Near Diagnosis.Journal of autism and developmental disorders · 2026Article
- Exploring the Association Between Parental Age and Autism Spectrum Disorder Risk in Qatar.Journal of autism and developmental disorders · 2026Article
- Risk factors and a prediction model for ASD symptoms in Chinese preschool children.Frontiers in psychiatry · 2026Article
- Review of Autism Spectrum Disorder (ASD): Epidemiology, Aetiology, Pathology, and Pharmacological Treatment.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Testing the Development of a Diet-Based Bisphenol a Score to Facilitate Studies on Child Neurodevelopment: A Pilot Project.International journal of environmental research and public health · 2025Article
- Female reproductive health trends and autism spectrum disorder prevalence between 2000 and 2024.Scientific reports · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThere has been conflicting evidence in earlier research on the association between parental age and autism risk. To clarify this association, we conducted a comprehensive meta-analysis of observational studies. The primary objective of this study was to determine the association between parents' age and the risk of autism in the offspring.
methodsPubMed, EMBASE and Web of Science were searched for reports published up to November 2023. Results from relevant studies were pooled using random effects models. Subgroup analyses and meta-regression were performed to examine heterogeneity between the studies. Studies were included in this meta-analysis that focused on children with autism and examined the relationship between parents' age (mother or father) and the risk of autism.The quality of studies was assessed using the Newcastle-Ottawa Scale (NOS).
resultsThis meta-analysis included 41 articles. The low age of mother (OR = 0.96, (95% CIs: 0.88-1.05) and father (OR = 1.11, (95% CIs: 0.98-1.24) was not significantly associated with lower risk of autism in children. Conversely, greater paternal and maternal ages were associated with an increased risk of autism in their children. The adjusted odds ratios for mothers' and fathers' ages were 1.47 (95% CIs: 1.33-1.62) and 1.51 (95% CIs: 1.40-1.62), respectively.
conclusionIncreased risk of autism in children is significantly associated with greater parents' ages. Further research is needed to gain further insight into the mechanisms responsible for the effects of parents' ages on the risk of autism in children. The findings of previous studies on the association between parents' ages and their children's autism risk have been mixed. Therefore, by carefully examining a number of previous investigations, in this study we aimed to determine the exact relationship between parental age and autism risk. According to the study's findings, parents who are older have a higher chance of their child getting autism. In other words, children of older parents are more likely to develop autism. The exact causes of this relationship, however, are still unclear. This study shows that higher age of parents can be one of the risk factors for autism in their childs.
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