Evidence map›Paper›PMID 39578823›Full record

SynthesisJournal of orthopaedic surgery and research2024

Ilizarov method combined with accordion technique for treating long bone defects in the lower limbs: a systematic review.

Zhiqiang Ren, Jinghong Yang, Zi Wang, Lujun Jiang, Lian Tang, Jiyuan Yan, Juncai Liu, Yanshi Liu, Zhong Li

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. [Advances on limb reconstruction technology for bone infection].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026
    Review
  2. Article
  3. Article
  4. [Effectiveness of staged therapy using external fixation frame for infectious nonunion near knee joint].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiqiang Ren *Department of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Jinghong Yang *Department of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Zi WangDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Lujun JiangDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Lian TangDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Jiyuan YanDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Juncai LiuDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China.
Yanshi LiuDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China. liuyanshi_1990@163.com.
Zhong LiDepartment of Orthopedics, Affiliated Hospital of Southwest Medical University, Lu Zhou, 646000, People's Republic of China. lzlizhong199403@163.com.

Funding

Sichuan Province Science and Technology Support Program,China 2022YFS0628The Key Research and Development Program of Sichuan Province 2023YFQ0009
6 · The paper itself

Abstract

backgroundBone defects and nonunion following initial treatment remain significant clinical challenges. The Ilizarov method constitutes a fundamental approach for addressing bone defects, and its integration with adjunctive techniques, such as the accordion maneuver, antibiotic spacers, or internal fixation, has become increasingly widespread. Despite this, limited research exists on the clinical outcomes specifically related to the use of the Ilizarov method combined with the accordion technique for treating long bone defects in the lower limbs.

objectiveThis study seeks to systematically review the application of the Ilizarov method in combination with the accordion technique for addressing long bone deficiencies in the lower limbs. STUDY

designSystematic review; Level of evidence, 4.

methodsA systematic review was performed in alignment with the PRISMA guidelines (Preferred Reporting Items for Systematic Reviews and Meta-Analyses), involving searches of Medline, Embase, Web of Science, and the Cochrane Library, with the search process concluding on August 20, 2024. The study population consisted of patients with bone defects who underwent treatment using the Ilizarov method in conjunction with the accordion technique. The methodological quality of the included studies was evaluated using the MINORS (Methodological Index for Non-Randomized Studies) scoring system. This study recorded and analyzed the participant count for each study that met the inclusion criteria, along with the number of patients who achieved bone healing, the bone and functional outcomes, and complications such as pin infections, pain, and refracture.

resultsDrawing from eight studies involving 80 patients with bone defects treated through the Ilizarov method combined with the accordion technique, this systematic review evaluated the method's impact on bone regeneration. Of these patients, 24% presented with femoral defects, while 76% had tibial defects. The mean patient age was 32.8 years, with an average follow-up of 25.2 months. The accordion technique involved daily distraction and compression adjustments ranging from 0.25 to 1 mm, typically in more than two cycles, effectively promoting bone healing. The bone healing rate was high, with the majority of patients rated as having excellent or good functional recovery, according to standards such as ASAMI and Paley. Common complications included superficial pin tract infections (33.75%) and deep pin tract infections (6.25%), both of which were generally manageable with routine treatment. The accordion technique showed promising results in shortening healing time and enhancing the quality of bone healing.

conclusionThis systematic review demonstrates that despite variations in parameter settings across studies, the Ilizarov method combined with the accordion technique consistently shows strong efficacy and safety in promoting bone regeneration and functional recovery. While some complications may arise, they are generally well-managed with standard care. This approach represents a reliable option for complex bone reconstruction, with future research needed to optimize parameters and further enhance clinical outcomes.

Indexed as

Ilizarov TechniqueAdultFemaleHumansLower ExtremityMaleTreatment OutcomeAccordion techniqueBone defectIlizarov methodInfectionNonunion

Identifiers

PMID39578823
PMCPMC11583378

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.