ArticleScientific reports2024
Scan speed affects quantitative optical coherence tomography angiography vascular metrics.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Does New Rapid Optical Coherence Tomography Angiography Acquisition Affect Image Quality in Healthy and Diseased Eyes?Translational vision science & technology · 2026Article
- APSified Peripapillary Vessel Density in Glaucoma Suspects and Open-Angle Glaucoma.Diagnostics (Basel, Switzerland) · 2026Article
- Quantitative Comparison of Two Novel Swept-Source Optical Coherence Tomography Angiography Devices.Diagnostics (Basel, Switzerland) · 2026Article
- Strip-Scanning for Efficient Widefield Retinal OCTA Mosaicking.Translational vision science & technology · 2026Article
- Impact of 85 kHz versus 125 kHz SHIFT OCTA scan speeds on image quality in retinal diseases and diagnostic reliability of choroidal neovascular membranes.Scientific reports · 2025Article
- Optical Coherence Tomography- and Optical Coherence Tomography Angiography-Based Evaluation in Treatment-Naïve Non-Exudative Macular Neovascularization.Journal of clinical medicine · 2025Article
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Authors and funding
5 authors.
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Abstract
Optical coherence tomography angiography (OCTA) offers the possibility of obtaining objective quantification of retinal vasculature, with increasing utility as biomarkers for both systemic and ocular diseases. However, the differences between different manufacturers and scan settings are still an important limitation, as many parameters could affect vessel quantification. Here we aim to study the influence of scan speed on quantitative vascular parameters using OCTA. 57 eyes in good retinal health received two consecutive 20 × 20° macular OCTA scans using SPECTRALIS SHIFT at different scan speeds: 85 and 125 kHz. Vessel density (VD) and vessel length density (VLD) in both the superficial (SVP) and deep vascular plexus (DVP), duration of the scan and Q-value were compared between scanning speeds. OCTA images taken at 85 kHz showed significantly higher VD and VLD values (% reduction in SVP: VD -4.03% to -5.8%, VLD - 4.96% to -6.07%; in DVP: VD -3.35% to -6.58%, VLD - 3.60% to -6.66%). At 125 kHz, acquisition time was reduced by 22%, but Q-values were lower (34.1 vs. 35.6). Thus, while higher A-scan rates reduce acquisition time, they lower VD and VLD in both plexus. Further studies in eyes with pathology are needed to better understand the magnitude of these changes.
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