Evidence map›Paper›PMID 39578521›Full record

ArticleMolecular psychiatry2025

The effects of adverse life events on brain development in the ABCD study®: a propensity-weighted analysis.

Amanda Elton, Ben Lewis, Sara Jo Nixon

Abstract read
In one paragraph

Article in Molecular psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. From adolescence to Alzheimer's: a neurodevelopmental lifespan model of cognitive vulnerability.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  2. Comprehensive social determinants of health and brain health in midlife.The journal of prevention of Alzheimer's disease · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Amanda EltonDepartment of Psychiatry, University of Florida, Gainesville, FL, 32610, USA. aelton@email.unc.edu.ORCID 0000-0001-9027-1442
Ben LewisDepartment of Psychiatry, University of Florida, Gainesville, FL, 32610, USA.
Sara Jo NixonDepartment of Psychiatry, University of Florida, Gainesville, FL, 32610, USA.

Funding

18/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT THE UNIVERSITY OF FLORIDAU01DA051016 · NIDA · UNIVERSITY OF FLORIDA · PI Linda B. Cottler, SARA JO NIXON · 2020 to 2026
$9.4M
The neural mechanisms of risk for alcohol use disorder among college studentsK01AA026334 · NIAAA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI ELTON, AMANDA L · 2018 to 2022
$770k
NIAAA NIH HHS K01 AA026334NIDA NIH HHS U01 DA051016
6 · The paper itself

Abstract

Longitudinal studies of the effects of adversity on human brain development are complicated by the association of stressful events with confounding variables. To counter this bias, we apply a propensity-weighted analysis of the first two years of The Adolescent Brain Cognitive Development

Indexed as

Adverse Childhood ExperiencesBrainAdolescentChildFemaleHumansLife Change EventsLongitudinal StudiesMachine LearningMagnetic Resonance ImagingMalePropensity ScoreStress, Psychological

Identifiers

PMID39578521
PMCPMC12984540

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.