ArticleScientific reports2024
Orbital computed tomography imaging characteristics of thyroid-associated ophthalmopathy.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Orbital computed tomography biomarkers for the assessment of activity of Thyroid Eye Disease.PloS one · 2026Article
- The impact of graves' orbitopathy on anterior segment structures and choroidal parameters.BMC ophthalmology · 2025Article
- Three-dimensional measurement and analysis of the compressor urethrae and urethra in postpartum women.Translational andrology and urology · 2025Article
- Advancements in imaging research in thyroid-associated ophthalmopathy.Frontiers in endocrinology · 2025Review
- MRI-based SIR quantitative biomarkers: a novel imaging diagnostic strategy for thyroid eye disease activity staging.Frontiers in endocrinology · 2025Article
- Extraocular muscle index as a novel indicator of inflammatory condition in graves' ophthalmopathy patients.Frontiers in endocrinology · 2025Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
This study aims to investigate the distribution characteristics and correlations of orbital soft tissue volume expansion in patients with thyroid-associated ophthalmopathy (TAO) by analyzing orbital computed tomography (CT) data and to determine the most appropriate parameters and corresponding cut-off values for imaging classification. Patients with TAO who met the inclusion and exclusion criteria, along with those with lacrimal duct obstruction requiring orbital CT examination, were included in the study. Raw CT data were imported into Mimics and RadiAnt software for analysis, and measurements of orbital volume, orbital fat volume, extraocular muscle volume, optic nerve volume, and exophthalmos were obtained. The results demonstrated that the combination of Mimics and other softwares for processing orbital CT scans allows for the quantitative analysis of various soft tissue volumes within the orbit. The MV/FV ratio was found to effectively reflect the relative changes in extraocular muscle volume, serving as a valuable indicator for identifying different subtypes of TAO and providing significant clinical reference value.
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Registered trials
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