ArticleNature communications2024
Prebiotic formation of enantiomeric excess D-amino acids on natural pyrite.
Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The selfish ribosome.PLoS biology · 2026Article
- Space ionizing radiation triggers the formation of peptides and organophosphates on olivine surfaces.Nature communications · 2026Article
- Dimensionally Resolved Nanostructures of an Atomically Precise and Optically Active 1D van der Waals Helix.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Symmetry Breaking of Molecules Triggered by Chiral Inorganic Nanostructures Without Organic Components.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
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Authors and funding
6 authors.
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Abstract
D-amino acids, found in excess in a minority of organisms and crucial for marine invertebrates, contrast with the more common L-amino acids in most life forms. The local prebiotic origin of D-amino acid enantiomeric excess in natural systems remains an unsolved conundrum. Herein, we demonstrate the formation of enantiomeric excess (ee) D-amino acids through photocatalytic reductive amination of α-keto acids on natural pyrite. Various amino acids with ee values in the range of 14.5-42.4%, are formed. The wavy arrangement of atoms on the surface of pyrite is speculated to lead to the preferential formation of D-amino acids. This work reveals the intrinsic asymmetric photocatalytic activity of pyrite, which could expand understandings on mechanism of asymmetric catalysis and chirality of inorganic crystals. Furthermore, it provides a plausible pathway for the prebiotic formation of D-amino acids, adding further evidence to the origin of D-amino acids enantiomeric excess in natural systems.
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