Evidence map›Paper›PMID 39576881›Full record

ArticleACS applied materials & interfaces2024

Biomolecule and Ion Releasing Mesoporous Nanoparticles: Nonconvergent Osteogenic and Osteo-immunogenic Performance.

Azin Khodaei, Qaisar Nawaz, Zhengqing Zhu, Saber Amin Yavari, Harrie Weinans, Aldo R Boccaccini

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Azin KhodaeiDepartment of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.ORCID 0000-0001-8729-3296
Qaisar NawazDepartment of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.ORCID 0000-0001-7068-2383
Zhengqing ZhuDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, The Netherlands.ORCID 0000-0002-0109-1771
Saber Amin YavariDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, The Netherlands.ORCID 0000-0003-1677-5751
Harrie WeinansDepartment of Orthopedics, University Medical Center Utrecht, 3508GA Utrecht, The Netherlands.ORCID 0000-0002-2275-6170
Aldo R BoccacciniDepartment of Materials Science and Engineering, Institute of Biomaterials, University of Erlangen-Nuremberg, 91058 Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune-involved cell communications have recently been introduced as key role players in the fate of mesenchymal stem cells in making bone tissue. In this study, a drug delivery system for bone (re)generation based on copper-doped mesoporous bioactive glass nanoparticles (BGNPs) was developed to codeliver copper as a biologically active ion and icariin as an anti-inflammatory agent. This design was based on temporal inflammation fluctuations from proinflammatory to anti-inflammatory during bone generation. Three

Indexed as

CopperFlavonoidsMesenchymal Stem CellsNanoparticlesOsteogenesisAnimalsAnti-Inflammatory AgentsHumansMacrophagesMicePorosityAnti-Inflammatory AgentsCopperFlavonoidsicariinBone regenerationFlavonoidImmunomodulatoryInflammationTissue engineering

Identifiers

PMID39576881
PMCPMC11647896

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.