Evidence map›Paper›PMID 39576485›Full record

ArticleOphthalmology and therapy2025

Ablation Depth-Dependent Survival Analysis of Phototherapeutic Keratectomy for Recurrent Corneal Erosion Syndrome.

Kunal A Gadhvi, Georgios Vakros, Alfredo Borgia, Kirithika Muthusamy, Laura de Benito-Llopis, Alexander C Day, Daniel M Gore

Abstract read
In one paragraph

Article in Ophthalmology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kunal A Gadhvi *Department of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.
Georgios Vakros *Department of Corneal and External Eye Diseases, Moorfields Eye Hospital, London, UK.
Alfredo BorgiaDepartment of Corneal Diseases, St. Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK. alfr.borgia@gmail.com.ORCID http://orcid.org/0000-0002-3976-242X
Kirithika MuthusamyDepartment of Corneal and External Eye Diseases, Moorfields Eye Hospital, London, UK.
Laura de Benito-LlopisDepartment of Corneal and External Eye Diseases, Moorfields Eye Hospital, London, UK.
Alexander C DayDepartment of Corneal and External Eye Diseases, Moorfields Eye Hospital, London, UK.
Daniel M GoreDepartment of Corneal and External Eye Diseases, Moorfields Eye Hospital, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPhototherapeutic keratectomy (PTK) is a treatment for recurrent corneal erosion syndrome (RCES). The aim of this study was to investigate whether deeper ablations yielded greater success rates.

methodsRetrospective case notes review with prospective patient-reported outcome measures for all patients who had undergone PTK for RCES at a single tertiary referral unit. Patients received treatment with the Schwind Amaris

resultsSeventy eyes of 63 patients were included for analysis, of whom 39 (56%) had preceding trauma and 20 (29%) had epithelial basement membrane dystrophy (EBMD), with the remaining 11 (15%) of unknown aetiology. Twenty eyes (29%) received an ablation ≥ 15 µm (mean ablation depth 16.85 ± 3.4 µm) and 50 (71%) received < 15 µm (mean ablation depth 9.26 ± 1.5 µm). Overall, 65 eyes (93%) reported a subjective improvement in symptoms, with 46 (66%) remaining completely symptom free at the last follow-up [mean follow-up 24 (range, 9-48) months]. Eighty-five per cent of eyes in the ≥ 15 µm group remained symptom free compared to 58% of those with < 15 µm (p = 0.036).

conclusionPTK is an effective treatment for RCES, with deeper ablations yielding longer symptom-free survival.

Indexed as

EBMDEpithelial basement membrane dystrophyPhototherapeutic keratectomyPTKRCESRecurrent corneal erosion syndrome

Identifiers

PMID39576485
PMCPMC11724826

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.