Evidence map›Paper›PMID 39576479›Full record

ArticleBulletin of experimental biology and medicine2024

Functional Assessment of Rat Sciatic Nerve Regeneration Using a Nerve Conduit Based on Ion Exchange Membrane.

T V Rusinova, K I Melkonyan, R A Vinogradov, A S Asyakina, S A Knyshova

Abstract read
PubMed Publisher
In one paragraph

Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

T V RusinovaKuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia. cnil.ksma@yandex.ru.
K I MelkonyanKuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
R A VinogradovKuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
A S AsyakinaKuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.
S A KnyshovaKuban State Medical University, Ministry of Health of the Russian Federation, Krasnodar, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The problem with modern nerve conduits is inability to transmit nerve impulses to the distal part of the damaged nerve. Cationic conductivity is a necessary characteristic of the nerve conduit ensuring effective regeneration of the peripheral nerves. We performed a functional assessment of the regeneration of rat sciatic nerve using a nerve conduit based on an ion-exchange membrane. A sciatic nerve defect was experimentally simulated in Wistar rats with further implantation of the LF-4SK membrane. On days 60 and 90 after surgery, the sciatic functional index and the ratio of the shin girth of the operated limb to the intact limb were calculated; on day 90, an electrophysiological assessment of nerve recovery was carried out. The results of the study showed that the conduit based on the LF-4SK membrane optimizes the functional recovery of the sciatic nerve defect.

Indexed as

Nerve RegenerationRats, WistarSciatic NerveAnimalsGuided Tissue RegenerationIon ExchangeMaleMembranes, ArtificialRatsRecovery of FunctionMembranes, Artificialelectrically conductive material; sciatic nerve damage; LF-4SK; nerve conduit

Identifiers

PMID39576479

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.