Evidence map›Paper›PMID 39576451›Full record

ArticleAnnals of surgical oncology2025

Disparities in Palliative Treatment Utilization in Metastatic Colorectal Cancer Patients.

Shaina Sedighim, Rhami Khorfan, Jordan Shin, Aaqil Khan, Yixuan Irene Tang, Amy Y Li, Maheswari Senthil, Michael P O'Leary, Oliver S Eng

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Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shaina SedighimDepartment of Surgery, University of California Irvine, Orange, CA, USA.
Rhami KhorfanDepartment of Surgery, Loma Linda University School of Medicine, Loma Linda, CA, USA.
Jordan ShinSchool of Medicine, University of California Irvine, Orange, CA, USA.
Aaqil KhanDepartment of Surgery, University of California Irvine, Orange, CA, USA.
Yixuan Irene TangDepartment of Surgery, University of California Irvine, Orange, CA, USA.
Amy Y LiDepartment of Surgery, University of California Irvine, Orange, CA, USA.
Maheswari SenthilDepartment of Surgery, University of California Irvine, Orange, CA, USA.
Michael P O'LearyDepartment of Surgery, University of California Irvine, Orange, CA, USA.
Oliver S EngDepartment of Surgery, University of California Irvine, Orange, CA, USA. oeng@hs.uci.edu.ORCID http://orcid.org/0000-0003-0226-5005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with metastatic colorectal cancer (mCRC) often require multidisciplinary interventions due to the diversity of symptoms. Palliative treatment offers benefits including improved quality of life, yet sociodemographic disparities influence its utilization. This study aims to characterize these disparities in palliative treatment use among mCRC patients.

methodsUtilizing data from the National Cancer Database, we identified patients diagnosed with mCRC between 2016 and 2020. Patients were categorized by metastatic site: peritoneal, liver, lung, or bone/brain/lymph node. Palliative treatment rates were compared across metastatic sites as well as patient and hospital factors.

resultsA total of 106,241 patients were identified as having mCRC, with 19,208 (18.08%) receiving palliative treatment; 24.0% of patients with multiple metastatic disease and 14.0% of those with solely peritoneal metastases (PM) utilized palliative treatment (p < 0.001). Furthermore, patients over 75 years of age had a significantly decreased likelihood of receiving palliative treatment compared with younger patients (p = 0.0002). Hispanic patients did not differ significantly from non-Hispanic White populations (p = 0.47). Those in the highest education quartile demonstrated a higher degree of palliative treatment use compared with the lowest education quartile (p = 0.0081).

conclusionAmong patients with mCRC, those with multiple sites of metastatic disease tend to receive higher rates of palliative treatment compared with those with oligometastatic disease. Patients with PM had the lowest rate of receiving palliative treatment. Other determinates of utilizing palliative treatment include younger age groups and higher education. Further research is warranted to understand the patterns of disparities in palliative treatment use among mCRC patients.

Indexed as

Colorectal NeoplasmsHealthcare DisparitiesPalliative CarePeritoneal NeoplasmsAdultAgedAged, 80 and overFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisQuality of LifeColon cancerHealthcare disparitiesPalliative treatmentPeritoneal metastasisSociodemographic disparities

Identifiers

PMID39576451

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.