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ArticleInternational urology and nephrology2025

Robot-assisted partial nephrectomy vs. percutaneous cryoablation for T1a renal tumors: a single-center retrospective analysis of outcomes and costs.

Vincenzo Iossa, Savio Domenico Pandolfo, Roberto Buonopane, Antonio Di Girolamo, Felice Fiore, Gaetano Sessa, Raffaele Vitale, Angelo Ferraro, Enrico Maria Amodeo, Piercarmine Porcaro and 3 more

Abstract readComparative Study
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In one paragraph

Article in International urology and nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Vincenzo IossaDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy. vincenzoiossa@msn.com.
Savio Domenico PandolfoDepartment of Urology, University of L'Aquila, 67100, L'Aquila, Italy.
Roberto BuonopaneDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Antonio Di GirolamoDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Felice FioreDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Gaetano SessaDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Raffaele VitaleDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Angelo FerraroDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Enrico Maria AmodeoDepartment of Radiology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Piercarmine PorcaroDepartment of Radiology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Ernesto PunziDepartment of Radiology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Giulio LombardiDepartment of Radiology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.
Vittorio ImperatoreDepartment of Urology, Azienda Ospedaliera "S.G. Moscati", Avellino, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to compare perioperative, functional, and oncological outcomes between robot-assisted partial nephrectomy (RAPN) and cryoablation (CRYO), based on a 3-year experience at our Institution. Additionally, a secondary aim is to conduct a comparative cost analysis between the two procedures.

methodsA retrospective analysis was conducted, including patients who underwent RAPN or CRYO between January 2020 and December 2023. Group 1 consisted of 59 patients who underwent RAPN, while Group 2 included 38 patients who had CRYO. The evaluation parameters included baseline characteristics, perioperative, functional, and oncological outcomes, as well as total hospitalization costs.

resultsOperative time (OT), average length of hospital stay (LOS), and emetic blood loss (EBL) were significantly lower in the CRYO group. Furthermore, CRYO showed a significantly lower rate of postoperative complications of any grade (7.8% vs 16.9%); however, this was associated with a considerably higher recurrence rate (5.7% vs 1.7%). No substantial differences were found in long-term functional outcomes (ΔeGFR). In terms of costs, CRYO was more cost-effective than RAPN (€5473 vs €10,672), although the gap was partially offset by a higher reimbursement "DRG" rate for robotic partial nephrectomy (€7386 vs €4384).

conclusionsRobot-assisted partial nephrectomy (RAPN) remains the preferred option for treating small renal masses (sRM), providing excellent oncological results and acceptable morbidity. However, percutaneous cryoablation is a valid alternative, particularly for patients unfit for surgery, as long as meticulous postoperative follow-up is carried out.

Indexed as

CryosurgeryKidney NeoplasmsNephrectomyRobotic Surgical ProceduresAgedCost-Benefit AnalysisFemaleHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesTreatment OutcomeClinical T1CryoablationKidney neoplasmsPartial nephrectomyRenal mass

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.