Evidence map›Paper›PMID 39576383›Full record

ArticleSleep & breathing = Schlaf & Atmung2024

Obstructive sleep apnea in 12 to 24 months old toddlers referred for sleep study in a tertiary care center.

Egambaram Senthilvel, Theresa Kluthe, Quang L Nguyen, Charmi Shah, Matthew Kinney, Claire Feller, Kelly Betz, Ganesh Sivaram, Kahir Jawad, Karim El-Kersh

Abstract read
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Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Egambaram SenthilvelDepartment of Pediatrics, University of Louisville and Norton Children Medical Group, 9880 Angies Way Suite 300, Louisville, Kentucky, KY 40241, USA. Egambaram.senthilvel@louisville.edu.
Theresa KlutheDepartment of Pediatrics, University of Louisville and Norton Children Medical Group, 9880 Angies Way Suite 300, Louisville, Kentucky, KY 40241, USA.
Quang L NguyenDepartment of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Louisville School Medicine, Louisville, Kentucky, USA.
Charmi ShahDepartment of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Matthew KinneyDepartment of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Claire FellerDepartment of Pediatrics, University of Louisville School of Medicine, Louisville, Kentucky, USA.
Kelly BetzDepartment of Pediatrics, Norton Children Medical Group, Louisville, Kentucky, USA.
Ganesh SivaramDepartment of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Louisville School Medicine, Louisville, Kentucky, USA.
Kahir JawadDepartment of Pediatrics, University of Louisville and Norton Children Medical Group, 9880 Angies Way Suite 300, Louisville, Kentucky, KY 40241, USA.
Karim El-KershDepartment of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, University of Arizona College of Medicine, Phoenix, Arizona, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess OSA prevalence, comorbidities, and the influence of sleep stages and body positions on respiratory events distribution in toddlers aged 12-24 months.

methodsA single center retrospective study that included toddlers aged 12-24 months old who underwent overnight PSG. OSA severity was categorized by obstructive apnea-hypopnea index (OAHI) as mild (1-4.9 events/h), moderate (5-9.9 events/h), and severe (≥ 10 events/h).

results283 PSG data were included with a median age of 18 months (IQR 16-20.25) for the OSA group (168/283) and 19 months (IQR 16-22) for the non-OSA group (115/283) (p = 0.047). OSA prevalence was 68.5% (42.3% mild, 18.5% moderate, and 39% severe). 38.1% of children had no comorbidities, 24.4% had a history of prematurity and 11.3% had Down syndrome. Multivariate binominal regression analysis showed that children with history of prematurity (p = 0.017) and Down syndrome (p = 0.043) had higher odds of having OSA. The mean SaO

conclusionIn toddlers aged 12-24 months, history of prematurity and Down syndrome were significantly associated with OSA. Obstructive respiratory events occurred predominantly in REM sleep, and no significant positional relations were noted.

Indexed as

PolysomnographySleep Apnea, ObstructiveTertiary Care CentersChild, PreschoolComorbidityDown SyndromeFemaleHumansInfantMaleRetrospective StudiesSleep Stages12-24 months toddlersObstructive sleep apneaPresentation polysomnogram findings management

Identifiers

PMID39576383

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.