Evidence map›Paper›PMID 39576009›Full record

ArticleGenetics2025

Global genotype by environment prediction competition reveals that diverse modeling strategies can deliver satisfactory maize yield estimates.

Jacob D Washburn, José Ignacio Varela, Alencar Xavier, Qiuyue Chen, David Ertl, Joseph L Gage, James B Holland, Dayane Cristina Lima, Maria Cinta Romay, Marco Lopez-Cruz and 49 more

Abstract read
In one paragraph

Article in Genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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  11. Order from entropy: big data from FAIR data cohorts in the digital age of plant breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  12. Breeding perspectives on tackling trait genome-to-phenome (G2P) dimensionality using ensemble-based genomic prediction.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

59 authors.

Jacob D WashburnUSDA-ARS, MWA-PGRU, 302-A Curtis Hall, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0003-0185-7105
José Ignacio VarelaDepartment of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, 1575 Linden Drive, Madison, WI 53706, USA.
Alencar XavierCorteva Agrisciences, 8305 NW 62nd Ave, Johnston, IA 50131, USA.ORCID 0000-0001-5034-9954
Qiuyue ChenDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0002-3304-8321
David ErtlIowa Corn Promotion Board, Johnston, IA 50131, USA.
Joseph L GageDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0001-5946-4414
James B HollandDepartment of Crop and Soil Sciences, North Carolina State University, Raleigh, NC 27695, USA.ORCID 0000-0002-4341-9675
Dayane Cristina LimaDepartment of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, 1575 Linden Drive, Madison, WI 53706, USA.
Maria Cinta RomayInstitute for Genomic Diversity, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-9309-1586
Marco Lopez-CruzDepartments of Epidemiology and Biostatistics and Statistics and Probability, and Institute for Quantitative Health Science and Engineering, Michigan State University, 775 Woodlot Dr, East Lansing, MI 48823, USA.ORCID 0000-0002-2548-1766
Gustavo de Los CamposDepartments of Epidemiology and Biostatistics and Statistics and Probability, and Institute for Quantitative Health Science and Engineering, Michigan State University, 775 Woodlot Dr, East Lansing, MI 48823, USA.ORCID 0000-0001-5692-7129
Wesley BarberCorteva Agrisciences, 8305 NW 62nd Ave, Johnston, IA 50131, USA.
Cristiano ZimmerCorteva Agrisciences, 8305 NW 62nd Ave, Johnston, IA 50131, USA.ORCID 0000-0002-2108-8529
Ignacio Trucillo SilvaCorteva Agrisciences, 8305 NW 62nd Ave, Johnston, IA 50131, USA.
Fabiani RochaCorteva Agrisciences, 8305 NW 62nd Ave, Johnston, IA 50131, USA.
Renaud RincentUniversité Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE-Le Moulon, 91190 Gif-sur-Yvette, France.ORCID 0000-0003-0885-0969
Baber AliUniversité Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE-Le Moulon, 91190 Gif-sur-Yvette, France.
Haixiao HuDepartment of Plant Sciences, University of California Davis, One Shield Drive, Davis, CA 95616, USA.ORCID 0000-0001-5888-4839
Daniel E RuncieDepartment of Plant Sciences, University of California Davis, One Shield Drive, Davis, CA 95616, USA.ORCID 0000-0002-3008-9312
Kirill GusevSmart Agri Labs, 2055 Limestone Rd STE 200-C, Wilmington, DE 19808, USA.
Andrei SlabodkinSmart Agri Labs, 2055 Limestone Rd STE 200-C, Wilmington, DE 19808, USA.
Phillip BaxSmart Agri Labs, 2055 Limestone Rd STE 200-C, Wilmington, DE 19808, USA.
Julie AubertUniversité Paris-Saclay, AgroParisTech, INRAE, UMR MIA Paris-Saclay, 91120 Palaiseau, France.
Hugo GangloffUniversité Paris-Saclay, AgroParisTech, INRAE, UMR MIA Paris-Saclay, 91120 Palaiseau, France.
Tristan Mary-HuardUniversité Paris-Saclay, INRAE, CNRS, AgroParisTech, GQE-Le Moulon, 91190 Gif-sur-Yvette, France.
Theodore VanrenterghemUniversité Paris-Saclay, AgroParisTech, INRAE, UMR MIA Paris-Saclay, 91120 Palaiseau, France.
Carles Quesada-TraverMolecular Plant Breeding, Institute of Agricultural Sciences, ETH Zurich, Universitätstrasse 2, CH-8092 Zurich, Switzerland.ORCID 0000-0002-5880-7902
Steven YatesMolecular Plant Breeding, Institute of Agricultural Sciences, ETH Zurich, Universitätstrasse 2, CH-8092 Zurich, Switzerland.
Daniel Ariza-SuárezMolecular Plant Breeding, Institute of Agricultural Sciences, ETH Zurich, Universitätstrasse 2, CH-8092 Zurich, Switzerland.
Argeo UlrichPuregene AG, Etzmatt 273, CH-4314 Zeiningen, Switzerland.
Michele WylerMWSchmid GmbH, Hauptstrasse 34, CH-8750 Glarus, Switzerland.ORCID 0000-0003-1097-5322
Daniel R KickUSDA-ARS, MWA-PGRU, 302-A Curtis Hall, University of Missouri, Columbia, MO 65211, USA.ORCID 0000-0002-9002-1862
Emily S BellisDepartment of Computer Science, Arkansas State University, 2105 E. Aggie Rd, Jonesboro, AR 72401, USA.
Jason L CauseyDepartment of Computer Science, Arkansas State University, 2105 E. Aggie Rd, Jonesboro, AR 72401, USA.
Emilio Soriano ChavezDepartment of Computer Science, Arkansas State University, 2105 E. Aggie Rd, Jonesboro, AR 72401, USA.
Yixing WangDepartment of Computer Science, Arkansas State University, 2105 E. Aggie Rd, Jonesboro, AR 72401, USA.
Ved PiyushDepartment of Statistics, University of Nebraska-Lincoln, 340 Hardin Hall North Wing, Lincoln, NE 68583, USA.
Gayara D FernandoDepartment of Statistics, University of Nebraska-Lincoln, 340 Hardin Hall North Wing, Lincoln, NE 68583, USA.
Robert K HuGenomics and Computational Biology, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA 19104, USA.
Rachit KumarGenomics and Computational Biology, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA 19104, USA.
Annan J TimonGenomics and Computational Biology, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA 19104, USA.
Rasika VenkateshGenomics and Computational Biology, Perelman School of Medicine at the University of Pennsylvania, University of Pennsylvania, 3700 Hamilton Walk, Philadelphia, PA 19104, USA.
Kenia Segura AbáDOE Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, MI 48824, USA.
Huan ChenGenetics and Genome Sciences Graduate Program, Michigan State University, East Lansing, MI 48824, USA.
Thilanka RanaweeraDOE Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, MI 48824, USA.
Shin-Han ShiuDOE Great Lakes Bioenergy Research Center, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0001-6470-235X
Peiran WangNC Plant Science Initiative, North Carolina State University, 840 Oval Drive, Raleigh, NC 27606, USA.
Max J GordonNC Plant Science Initiative, North Carolina State University, 840 Oval Drive, Raleigh, NC 27606, USA.
B Kirtley AmosNC Plant Science Initiative, North Carolina State University, 840 Oval Drive, Raleigh, NC 27606, USA.
Sebastiano BusatoNC Plant Science Initiative, North Carolina State University, 840 Oval Drive, Raleigh, NC 27606, USA.
Daniel PerondiNC Plant Science Initiative, North Carolina State University, 840 Oval Drive, Raleigh, NC 27606, USA.
Abhishek GognaDepartment of Breeding Research, Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung, Corrensstraße 3, Gatersleben 6466, Germany.ORCID 0000-0002-5990-1829
Dennis PsaroudakisDepartment of Molecular Genetics, Leibniz-Institut für Pflanzengenetik und Kulturpflanzenforschung, Corrensstraße 3, Gatersleben 6466, Germany.
Chun-Peng James ChenSchool of Animal Sciences, Virginia Tech, Blacksburg, VA 24061, USA.
Hawlader A Al-MamunSchool of Biological Sciences and Centre of Applied Bioinformatics, University of Western Australia, Perth, WA 6009, Australia.
Monica F DanileviczSchool of Biological Sciences and Centre of Applied Bioinformatics, University of Western Australia, Perth, WA 6009, Australia.
Shriprabha R UpadhyayaSchool of Biological Sciences and Centre of Applied Bioinformatics, University of Western Australia, Perth, WA 6009, Australia.
David EdwardsSchool of Biological Sciences and Centre of Applied Bioinformatics, University of Western Australia, Perth, WA 6009, Australia.ORCID 0000-0001-7599-6760
Natalia de LeonDepartment of Plant and Agroecosystem Sciences, University of Wisconsin-Madison, 1575 Linden Drive, Madison, WI 53706, USA.ORCID 0000-0001-7867-9058

Funding

Characterizing and modeling the genomewide molecular basis of gene-environment interactionsR35GM151048 · NIGMS · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI Joseph Lee Gage · 2023 to 2026
$1.5M
Agriculture and Food Research Initiative 2020-67013-30904Iowa Corn Promotion BoardNational Corn Growers AssociationNational Institute of Food and Agriculture Hatch 7002327National Institute of General Medical Sciences of the National Institutes of Health R35GM151048NIGMS NIH HHS R35 GM151048NSF PGRP-Tech #2035472United States Department of Agriculture's Agricultural Research Service 5070-21000-041-000-DUSDA-Agricultural Research ServiceUSDA National Institute of Food and AgricultureUS Department of Agriculture
6 · The paper itself

Abstract

Predicting phenotypes from a combination of genetic and environmental factors is a grand challenge of modern biology. Slight improvements in this area have the potential to save lives, improve food and fuel security, permit better care of the planet, and create other positive outcomes. In 2022 and 2023, the first open-to-the-public Genomes to Fields initiative Genotype by Environment prediction competition was held using a large dataset including genomic variation, phenotype and weather measurements, and field management notes gathered by the project over 9 years. The competition attracted registrants from around the world with representation from academic, government, industry, and nonprofit institutions as well as unaffiliated. These participants came from diverse disciplines, including plant science, animal science, breeding, statistics, computational biology, and others. Some participants had no formal genetics or plant-related training, and some were just beginning their graduate education. The teams applied varied methods and strategies, providing a wealth of modeling knowledge based on a common dataset. The winner's strategy involved 2 models combining machine learning and traditional breeding tools: 1 model emphasized environment using features extracted by random forest, ridge regression, and least squares, and 1 focused on genetics. Other high-performing teams' methods included quantitative genetics, machine learning/deep learning, mechanistic models, and model ensembles. The dataset factors used, such as genetics, weather, and management data, were also diverse, demonstrating that no single model or strategy is far superior to all others within the context of this competition.

Indexed as

Gene-Environment InteractionModels, GeneticZea maysGenotypePhenotypePlant Breedingcompetitiongenotype by environmentmaizephenotypepredictionyield

Identifiers

PMID39576009
PMCPMC12054733

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.