Evidence map›Paper›PMID 39575361›Full record

ArticleCureus2024

Hidden in Plain Sight: Antisynthetase Syndrome Masquerading As Acute Coronary Syndrome and Heart Failure.

Ahmed Fadel, Rekha Bhalla, Sarmad Mushtaq

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ahmed FadelRespiratory Medicine, Dartford and Gravesham National Health Service (NHS) Trust, Dartford, GBR.
Rekha BhallaRespiratory Medicine, Dartford and Gravesham National Health Service (NHS) Trust, Dartford, GBR.
Sarmad MushtaqRespiratory Medicine, Dartford and Gravesham National Health Service (NHS) Trust, Dartford, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A middle-aged man presented with fever, generalized myalgia, dyspnea, and worsening chest discomfort. Initial investigations showed elevated troponin and creatinine kinase levels and nonspecific ECG changes. Pulmonary embolism was ruled out, and high-resolution CT (HRCT) revealed ground-glass opacities and nonspecific interstitial pneumonia (NSIP)/organizing pneumonia (OP) overlap pattern. Given the elevated creatinine kinase level, antisynthetase syndrome with rapidly progressive interstitial lung disease (RP-ILD) was suspected. Treatment with pulse-dose methylprednisolone and tacrolimus led to significant clinical improvement, with HRCT showing resolution of the NSIP/OP findings on follow-up. This case highlights the importance of early diagnosis and multidisciplinary management in antisynthetase syndrome.

Indexed as

anti-jo-1 antibodiesantisynthetase syndromeconnective tissue disease associated interstitial lung diseasehigh-dose methylprednisolones: dermatomyositistacrolimus

Identifiers

PMID39575361
PMCPMC11581142

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.