Evidence map›Paper›PMID 39575089›Full record

ArticleOxford medical case reports2024

Rupioid psoriasis, a unique presentation treated with Ustekinumab.

Sdrah Diab, Moatasem Hussein Al-Janabi, Ibrahim Diab, Fouz Hassan

Abstract readCase Reports
In one paragraph

Article in Oxford medical case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sdrah DiabDepartment of Dermatology and sexually transmitted disease, Tishreen University Hospital, Lattakia, Syria.
Moatasem Hussein Al-JanabiDepartment of Pathology, Cancer Research Center, Tishreen University Hospital, Lattakia, Syria.ORCID https://orcid.org/0000-0003-1675-4125
Ibrahim DiabDepartment of Pediatrics, Tishreen University Hospital, Lattakia, Syria.
Fouz HassanDepartment of Dermatology, Tishreen University Hospital, Lattakia, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rupioid psoriasis is a rare subtype of psoriasis characterized by distinctive lesions resembling oyster shells, known as rupioid lesions. This subtype is particularly uncommon in the pediatric population and is often associated with poor treatment compliance. Ustekinumab, an IgG monoclonal antibody, targets IL-12 and IL-23, reducing the release of proinflammatory cytokines TNFα, IL-2, and IL-17α, which play vital roles in psoriasis pathophysiology. Approved for pediatric patients aged six years and older, ustekinumab provides a therapeutic option for moderate to severe psoriasis. We present the case of a 10-year-old girl diagnosed with psoriasis vulgaris at age two. She presented with rupioid lesions following a urinary tract infection that had been treated with oral cefixime (200 mg). After conducting appropriate tests, ustekinumab (45 mg subcutaneously) was administered, leading to significant improvements in the thickness of the lesions and overall appearance. This case demonstrates ustekinumab's efficacy in treating this challenging form of psoriasis.

Indexed as

childhood psoriasisinflammatory cytokinesmonoclonal antibodyPediatricpsoriasis treatmentRupioid psoriasisUstekinumab

Identifiers

PMID39575089
PMCPMC11576555

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.