Evidence map›Paper›PMID 39575023›Full record

ArticleCureus2024

Recurrent Aseptic (Mollaret) Meningitis: A Case Report.

Lauren B Querin, Wayne A Martini, Byron S Parker

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lauren B QuerinEmergency Medicine, Mayo Clinic Arizona, Phoenix, USA.
Wayne A MartiniEmergency Medicine, Mayo Clinic Arizona, Phoenix, USA.
Byron S ParkerEmergency Medicine, Veterans Affairs Medical Center, Prescott, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mollaret meningitis is a rare form of recurrent, self-resolving, aseptic meningitis with a high rate of return. Although it has been associated with several conditions, herpes simplex virus type 2 (HSV-2) is most common. Diagnosis requires recurrent (>3) episodes of aseptic meningitis as defined by pleocytosis in cerebrospinal fluid (CSF) with negative bacterial cultures. Management is controversial but focuses primarily on supportive care with a potential role for antiviral therapy in both treatment and prevention of recurrence. This case describes a 35-year-old male with fourteen prior episodes of meningitis presenting with a recurrence of symptoms. CSF studies showed an aseptic meningitis due to HSV-2. He was treated with antiviral therapy and ultimately discharged on daily valacyclovir for recurrence prevention. Increased awareness of this condition amongst emergency physicians may help reduce resource utilization and unnecessary antibiotics, while also enhancing appropriate follow-up and prevention of recurrence.

Indexed as

aseptic meningitiscsf pleocytosisherpes simplex virus type 2mollaret meningitisrecurrent headache

Identifiers

PMID39575023
PMCPMC11581458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.