Evidence map›Paper›PMID 39575002›Full record

ReviewCureus2024

Could the Arginine-Fluoride Association Have a Real Impact on Caries Prevention?

Sara El Harram, Tarik Sqalli

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sara El HarramConservative Dentistry and Endodontics, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fes, MAR.
Tarik SqalliLaboratory of Epidemiology and Research in Health Sciences, Faculty of Medicine, Pharmacy and Dentistry, Sidi Mohamed Ben Abdellah University, Fes, MAR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the context of preventive therapy, fluoride has allowed the reduction of the incidence and prevalence of caries. The establishment of the protective role of arginine in the neutralization of plaque acids has led to the development of new arginine-fluorine associations to potentiate this preventive aspect. Studies have reported that this association could provide superior efficacy compared to fluoride alone. A synergistic effect that could be potential and thus represent a promising ecological approach for caries prevention. However, confirmation of the effective efficacy of the arginine-fluoride association requires additional clinical studies to be carried out before establishing recommendations.

Indexed as

arginineassociationbiological approachcaries preventionfluoridetoothpastevarnish

Identifiers

PMID39575002
PMCPMC11581447

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.