Evidence map›Paper›PMID 39574999›Full record

ReviewCureus2024

Vaping Possible Negative Effects on Lungs: State-of-the-Art From Lung Capacity Alteration to Cancer.

Fakher Rahim, Karlygash Toguzbaeva, Dmitriy Sokolov, Kenesh O Dzhusupov, Abzal Zhumagaliuly, Ainur Tekmanova, Elmira Kussaiynova, Aiya Katayeva, Sholpan Orazbaeva, Aidana Bayanova and 3 more

Abstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Fakher RahimDepartment of Medical Laboratory Technologies, Alnoor University, Mosul, IRQ.
Karlygash ToguzbaevaDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Dmitriy SokolovDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Kenesh O DzhusupovPublic Health Sciences, International Higher School of Medicine, Bishkek, KGZ.
Abzal ZhumagaliulyDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Ainur TekmanovaDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Elmira KussaiynovaDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Aiya KatayevaDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Sholpan OrazbaevaDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Aidana BayanovaDepartment of Public Health, Asfendiyarov Kazakh National Medical University, Almaty, KAZ.
Mariyam OlzhasBiology, Haileybury Astana School, Astana, KAZ.
Alina ZhumataevaBiology, School-Gymnasium #22, Astana, KAZ.
Sabina MoldabekovaBiology, School-Gymnasium #22, Astana, KAZ.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaping has emerged as a popular alternative to traditional smoking. It produces smokeless vapour by heating an e-liquid mixture in an atomizer. This paper delves into the current state of knowledge surrounding electronic cigarettes, exploring the gap between the perceived safety of e-liquids and the emerging evidence of their harmful effects when inhaled. As we navigate this intricate landscape, it is crucial to unravel the complexities of vaping and its implications for public health. We conducted a three-layer systematic review of the guidelines set by the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) and Meta-analyses of Observational Studies in Epidemiology (MOOSE). The search was performed in three layers, including the first layer, the effect of vaping on lung function; the second layer, the effect of vaping on lung structure and inducing lung injury; and the third layer, the physiopathologic effect of vaping on the lung and a possible carcinogenic effect. Exposure to e-cigarette vapour reduced lung ventilation in adult male Long-Evans rats, indicating impaired lung function. In male Wistar rats, vaping was associated with a decrease in lung air volume and denser lung tissue structure. Studies on guinea pigs showed that vaping caused acute bronchoconstriction, contributing to lung function impairment. A case study of a young man with an E-cigarette and vaping-induced lung injury (EVALI) highlighted the detrimental effects of vaping on human lung function. The EVALI outbreak in the USA was linked to harmful substances in vapes, such as vitamin E acetate and THC, leading to serious lung injuries, including pneumonia and bronchiolitis. Vaping poses significant health risks, especially to young adults, and misconceptions regarding its safety persist despite evidence of its potential to cause various lung diseases. While vaping has positioned itself as a smoking cessation aid, the discussion surrounding its impact on lung health requires careful consideration. The lack of conclusive evidence on the long-term effects of vaping underscores the need for further research. However, existing data suggest that vaping is not without risks, and its potential association with respiratory issues and cancer underscores the urgency of public health interventions.

Indexed as

cancerelectronic cigaretteslung functionlung injuryvape

Identifiers

PMID39574999
PMCPMC11580103

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.