The impact of blood viscosity modeling on computational fluid dynamic simulations of pediatric patients with Fontan circulation.

Heng Wei, Coskun Bilgi, Kellie Cao, Jon A Detterich, Niema M Pahlevan, Andrew L Cheng

Abstract read

In one paragraph

Article in Physics of fluids (Woodbury, N.Y. : 1994), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Significance of Reynolds Number Consistency in Non-Newtonian Hemodynamic Simulations: Insights from Fontan Circulation.Physics of fluids (Woodbury, N.Y. : 1994) · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Heng WeiDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0002-3575-7420

Coskun BilgiDepartment of Aerospace and Mechanical Engineering, University of Southern California, Los Angeles, California, USA.ORCID https://orcid.org/0000-0003-0231-4727

Kellie CaoDepartment of Biomedical Engineering, University of Southern California, Los Angeles, California, USA.

Jon A DetterichORCID https://orcid.org/0000-0002-2086-9569

Niema M PahlevanORCID https://orcid.org/0000-0001-7498-0396

Andrew L ChengORCID https://orcid.org/0000-0002-4860-6218

Funding

Impact of Blood Viscosity and Vascular Compliance on Fontan Circulation Dysfunction in ChildrenK23HL161310 · NHLBI · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Andrew L Cheng · 2022 to 2026

$849k

NHLBI NIH HHS K23 HL161310

6 · The paper itself

Abstract

For univentricular heart patients, the Fontan circulation presents a unique pathophysiology due to chronic non-pulsatile low-shear-rate pulmonary blood flow, where non-Newtonian effects are likely substantial. This study evaluates the influence of non-Newtonian behavior of blood on fluid dynamics and energetic efficiency in pediatric patient-specific models of the Fontan circulation. We used immersed boundary-lattice Boltzmann method simulations to compare Newtonian and non-Newtonian viscosity models. The study included models from twenty patients exhibiting a low cardiac output state (cardiac index of 2 L/min/m

Identifiers

PMID39574945

DOI10.1063/5.0236095

PMCPMC11577338

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.