ArticlebioRxiv : the preprint server for biology2024
Discovery of a single-subunit oligosaccharyltransferase that enables glycosylation of full-length IgG antibodies in
Belen Sotomayor, Thomas C Donahue, Sai Pooja Mahajan, May N Taw, Sophia W Hulbert, Erik J Bidstrup, D Natasha Owitipana, Alexandra Pang, Xu Yang, Souvik Ghosal and 6 more
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
16 authors.
Belen SotomayorRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-3786-7252 Thomas C DonahueDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Sai Pooja MahajanDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0000-0002-4228-0341 Sophia W HulbertBiochemistry, Molecular and Cell Biology, Cornell University, Ithaca, NY 14853, USA.
Erik J BidstrupRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0001-9014-2042 D Natasha OwitipanaDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.
Alexandra PangRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.
Xu YangComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia 30602-4712, USA.
Souvik GhosalDepartment of Chemistry and Chemical Biology, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-2412-0544 Christopher A AlabiRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-2654-018X Parastoo AzadiComplex Carbohydrate Research Center, University of Georgia, 315 Riverbend Road, Athens, Georgia 30602-4712, USA.ORCID 0000-0002-6166-9432 Jeffrey J GrayDepartment of Chemical and Biomolecular Engineering, Johns Hopkins University, Baltimore, Maryland 21218, USA.ORCID 0000-0001-6380-2324 Lai-Xi WangDepartment of Chemistry and Biochemistry, University of Maryland, College Park, MD 20742, USA.ORCID 0000-0003-4293-5819 Matthew P DeLisaRobert Frederick Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0003-3226-1566 Funding
National Glycoscience Resource- CCRC Service and Training - NGlycoR@CCRCR24GM137782 · NIGMS · UNIVERSITY OF GEORGIA · PI Parastoo Azadi · 2020 to 2026
$5.2MCovergent Chemoenzymatic Synthesis of Glycopeptides and GlycoproteinsR01GM080374 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI WANG, LAI-XI · 2007 to 2021
$3.9MTraining future leaders at the chemistry-biology interfaceT32GM138826 · NIGMS · CORNELL UNIVERSITY · PI Jeremy Baskin · 2021 to 2026
$2.6MTechnologies to predict and probe glycosyl transferR01GM127578 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI GRAY, JEFFREY J · 2018 to 2020
$1.6MImmuno-Engineering: Integrated Engineering and Immunology TrainingT32EB023860 · NIBIB · CORNELL UNIVERSITY · PI AUGUST, AVERY, PUTNAM, DAVID A · 2018 to 2022
$933kNIBIB NIH HHS T32 EB023860NIGMS NIH HHS R01 GM080374NIGMS NIH HHS R01 GM127578NIGMS NIH HHS R24 GM137782NIGMS NIH HHS T32 GM138826
6 · The paper itselfAbstract
Human immunoglobulin G (IgG) antibodies are one of the most important classes of biotherapeutic agents and undergo glycosylation at the conserved N297 site in the C
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PMID39574765
PMCPMC11580905
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