Evidence map›Paper›PMID 39574602›Full record

ArticlebioRxiv : the preprint server for biology2024

Nagham Khouri-Farah, Qiuxia Guo, Thomas A Perry, Ryan Dussault, James Y H Li

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nagham Khouri-FarahDepartment of Genetics and Genome Sciences, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-6403, USA.
Qiuxia GuoDepartment of Genetics and Genome Sciences, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-6403, USA.
Thomas A PerryDepartment of Genetics and Genome Sciences, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-6403, USA.
Ryan DussaultDepartment of Genetics and Genome Sciences, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-6403, USA.
James Y H LiDepartment of Genetics and Genome Sciences, University of Connecticut School of Medicine, 263 Farmington Avenue, Farmington, CT 06030-6403, USA.ORCID 0000-0002-9231-2698

Funding

Combinatorial function of Foxp1/2/4 in Purkinje cell diversification and cerebellar developmentR01NS120556 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LI, JAMES Y.H · 2021 to 2025
$2.6M
MOLECULAR REGULATION OF LINEAGE SPECIFICATION OF THE MOUSE CEREBELLUMR01NS106844 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LI, JAMES Y.H · 2018 to 2022
$2.1M
Molecular Mechanisms and Heterogeneity in the Inferior Olivary Nucleus DevelopmentR21NS139034 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI LI, JAMES Y.H · 2024 to 2024
$458k
Studying the Molecular Mechanism of Foxp1/2 Function Controlling the Cerebellar DevelopmentF31NS124264 · NINDS · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI FARAH, NAGHAM · 2021 to 2023
$128k
NINDS NIH HHS F31 NS124264NINDS NIH HHS R01 NS106844NINDS NIH HHS R01 NS120556NINDS NIH HHS R21 NS139034
6 · The paper itself

Abstract

Mammalian cerebellar development is thought to be influenced by distinct Purkinje cell (PC) subtypes. However, the degree of PC heterogeneity and the molecular drivers of this diversity have remained unclear, hindering efforts to manipulate PC diversification and assess its role in cerebellar development. Here, we demonstrate the critical role of

Indexed as

cell fate specificationForkhead transcription factorshumanmousesingle-cell RNA-seq

Identifiers

PMID39574602
PMCPMC11581015

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.