Evidence map›Paper›PMID 39574480›Full record

ArticleImaging neuroscience (Cambridge, Mass.)2023

FastSurfer-HypVINN: Automated sub-segmentation of the hypothalamus and adjacent structures on high-resolutional brain MRI.

Santiago Estrada, David Kügler, Emad Bahrami, Peng Xu, Dilshad Mousa, Monique M B Breteler, N Ahmad Aziz, Martin Reuter

Abstract read
In one paragraph

Article in Imaging neuroscience (Cambridge, Mass.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Hypothalamus and intracranial volume segmentation at the group level by use of a Gradio-CNN framework.International journal of computer assisted radiology and surgery · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Tractometry of Human Visual White Matter Pathways in Health and Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
  12. Brain Volume Loss After Stereotactic Laser Interstitial Thermal Therapy in Patients With Temporal Lobe Epilepsy.Journal of neuroimaging : official journal of the American Society of Neuroimaging
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Santiago EstradaAI in Medical Imaging, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
David KüglerAI in Medical Imaging, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Emad BahramiAI in Medical Imaging, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Peng XuPopulation Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Dilshad MousaPopulation Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Monique M B BretelerPopulation Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
N Ahmad AzizPopulation Health Sciences, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.
Martin ReuterAI in Medical Imaging, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.

Funding

Mapping the Human Connectome: Structure, Function, and HeritabilityU54MH091657 · NIMH · WASHINGTON UNIVERSITY · PI UGURBIL, KAMIL, VAN ESSEN, DAVID C · 2010 to 2014
$34.7M
Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2020 to 2026
$10.9M
Deep Learning Algorithms for FreeSurferR01AG064027 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI FISCHL, BRUCE · 2020 to 2024
$3.4M
Novel Bioinformatics Strategies to Study Associations Between Genetic Variants and Neuroanatomical ShapeR01LM012719 · NLM · CORNELL UNIVERSITY · PI SABUNCU, MERT RORY · 2017 to 2020
$1.4M
Imaging the neurodevelopmental trajectory of depression and anxiety disorders with HCP protocolsR56MH121426 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI WHITFIELD-GABRIELI, SUSAN, YENDIKI, ANASTASIA · 2020 to 2020
$1.2M
NIA NIH HHS R01 AG064027NIBIB NIH HHS P41 EB030006NIMH NIH HHS R56 MH121426NIMH NIH HHS U54 MH091657NLM NIH HHS R01 LM012719
6 · The paper itself

Abstract

The hypothalamus plays a crucial role in the regulation of a broad range of physiological, behavioral, and cognitive functions. However, despite its importance, only a few small-scale neuroimaging studies have investigated its substructures, likely due to the lack of fully automated segmentation tools to address scalability and reproducibility issues of manual segmentation. While the only previous attempt to automatically sub-segment the hypothalamus with a neural network showed promise for 1.0 mm isotropic T1-weighted (T1w) magnetic resonance imaging (MRI), there is a need for an automated tool to sub-segment also high-resolutional (HiRes) MR scans, as they are becoming widely available, and include structural detail also from multi-modal MRI. We, therefore, introduce a novel, fast, and fully automated deep-learning method named

Indexed as

deep learninghetero-modalhigh-resolutionhypothalamic sub-segmentationstructural MRI

Identifiers

PMID39574480
PMCPMC11576934

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.