Evidence map›Paper›PMID 39574281›Full record

ArticleThe Journal of frailty & aging2024

Application of a Social Vulnerability Index and Its Associations with Physical Frailty and Disability in a Cross-sectional Study of Older Kenyan Women Living with and without HIV.

S Prabhu, B Oyaro, G Wanje, F M Aunon, N Gomez Juarez, B P Flaherty, W McCormick, M K Andrew, W Jaoko, R S McClelland and 1 more

Abstract read
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Article in The Journal of frailty & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

S PrabhuSandeep Prabhu, MD, MPH, MS, Brigham and Women's Hospital, 800 Huntington Ave, Boston, MA, 02115. Telephone 650-245-7276. Email: sprabhu4@bwh.harvard.edu; Alternate author: Susan M Graham, MD, MPH, PhD, University of Washington, 325 Ninth Avenue, Box 359909, Seattle, WA, 98104. Telephone: 206-351-0414. Email: grahamsm@uw.edu.
B Oyaro
G Wanje
F M Aunon
N Gomez Juarez
B P Flaherty
W McCormick
M K Andrew
W Jaoko
R S McClelland
S M Graham

Funding

University of Washington Developmental AIDS Research Center for Mental Health (UW ARCH)P30MH123248 · NIMH · UNIVERSITY OF WASHINGTON · PI SIMONI, JANE M. · 2021 to 2024
$5.8M
Social Frailty among Older Kenyan Women Living with and without HIV InfectionR21AG063602 · NIA · UNIVERSITY OF WASHINGTON · PI GRAHAM, SUSAN MARIE · 2019 to 2020
$428k
NIA NIH HHS R21 AG063602NIMH NIH HHS P30 MH123248
6 · The paper itself

Abstract

backgroundSocial vulnerability reflects deficits in social resources that may disproportionally impact older women with HIV (WWH) in Africa.

objectiveTo examine the relationship between scores on an adapted Social Vulnerability Index (SVI) and measures of physical frailty and disability.

designCross-sectional study.

participants293 women (156 HIV-positive, 137 HIV-negative) aged >40 years in Mombasa, Kenya who were recruited from the Mombasa Cohort of women with a history of transactional sex and the general community. MEASUREMENTS: Assessments including an SVI adapted for the Kenyan context (SVI-Kenya), the Clinical Frailty Scale (CFS) and the World Health Organization Disability Assessment (WHODAS) were compared by HIV status. Linear regression was used to determine the relationship between SVI-Kenya score and both CFS and WHODAS, after adjustment for potential confounders. An exploratory analysis identified factors associated with SVI-Kenya score. An age-by-HIV-status interaction term was tested and retained if significant in unadjusted analyses.

resultsMean SVI-Kenya score was 34.1 (SD, 12.9) and did not differ by HIV status (p=0.49). In adjusted analyses, each increment in SVI-Kenya score was associated with a 1.10-point higher WHODAS score (95%CI:0. 21, 1.99), but not with CFS. In exploratory analysis, factors associated with higher SVI-Kenya score included WHODAS score (adjusted beta=0.20; 95%CI: 0.05,0.35) and Mombasa Cohort recruitment (adjusted beta=5.91; 95%CI: 2.07,9.75). Being married, separated/divorced, or widowed predicted lower SVI-Kenya scores (by 5.52-9.09 points) compared to being single. Age did not predict SVI-Kenya score.

conclusionSocial vulnerability as measured by the SVI-Kenya score was associated with greater disability but not physical frailty. Social vulnerability was also associated with prior sex work and never having married. Our findings suggest that social vulnerability is a distinct construct from physical frailty among older Kenyan women and not related to HIV status.

Indexed as

FrailtyHIV InfectionsPersons with DisabilitiesSocial VulnerabilityAdultAgedCross-Sectional StudiesDisability EvaluationFemaleFrail ElderlyGeriatric AssessmentHumansKenyaMiddle Agedclinical frailtydisability, older womenHIVKenyaolder womensocial vulnerability

Identifiers

PMID39574281
PMCPMC12278831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.