Evidence map›Paper›PMID 39574036›Full record

Trial reportBMC anesthesiology2024

Comparison between ultrasound guided erector spinae plane block and paravertebral block on acute and chronic post mastectomy pain after modified radical mastectomy: randomized controlled trial.

Samy Abdelrahman Amr, Ahmed Hassan Othman, Eman Hassan Ahmed, Romany Gergis Naeem, Shereen Mamdouh Kamal

2 registry-linked trialsAbstract readRandomized Controlled TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04498234 naunknown statusnot on this map

Comparison Between Ultrasound Guided Erector Spinae Plane Block and Paravertebral Block on Acute and Chronic Postmastectomy Pain

TypeinterventionalSponsorSouth Egypt Cancer InstituteRan2020 to 2023Enrolled108ConditionsComparison Between Ultrasound Guided Erector Spinae Plane Block and Para-vertebral Block on Acute and Chronic Post Mastectomy PainArmsultrasound guided erector spinae plane block with bupivacaine 0.25% And ultrasound guided Paraveretebral block with bupivacaine 0.25 %
NCT07560267 narecruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Ultrasound-Guided Erector Spinae Plane Block in Postoperative Pain Management in Nephrectomy: A Randomized Controlled Trial

TypeinterventionalSponsorBangladesh Medical UniversityRan2025 to 2026Enrolled66ConditionsErector Spinae Plane Block, Nephrectomy, Postoperative PainArmsUltrasound-Guided Erector Spinae Plane (ESP) Block
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samy Abdelrahman AmrAnesthesia, Intensive Care and Pain Management Department, Faculty of Medicine, Assiut University, Assiut, Egypt.
Ahmed Hassan OthmanAnesthesia, Intensive Care and Pain Management Department, South Egypt Cancer institute, Assiut university, Assiut, Egypt.
Eman Hassan AhmedClinical Pathology South Egypt Cancer Institute Assiut University, Assiut, Egypt.
Romany Gergis NaeemAnesthesia, Intensive Care and Pain Management Department, South Egypt Cancer institute, Assiut university, Assiut, Egypt.
Shereen Mamdouh KamalAnesthesia, Intensive Care and Pain Management Department, South Egypt Cancer institute, Assiut university, Assiut, Egypt. shereenmamdouh@aun.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInadequate acute postoperative pain management is linked to the effect on the stress response and development of chronic pain. A unique regional anaesthetic method that is becoming more important for postoperative pain management is erector spinea plane block (ESP). Since its initial description, physicians have questioned weather this novel easy method can take the place of paravertebral block (PVB). Our goal was to evaluate, in contrast to control group, the effects of ESP & PVB on acute and chronic post-mastectomy pain.

methodsOne hundred and five female patients undergoing modified radical mastectomy participated in this study, randomly allocated into three equal groups: erector spinae plane block (ESP), thoracic paravertebral (TPV), and control groups. Both blocks were ultrasound-guided with 20 ml 0.25% bupivacaine according to patients' group, control group was administered standard general anaesthesia without intervention. Total morphine consumption in the first 24 h postoperative was the primary outcome. The secondary outcomes were time to the first analgesia, (Visual Analogue Scale)VAS score, serum level of cortisol and prolactin, sedation score, side effects, and LANSS scores in the first, third, and sixth postoperative months were among the variables compared between groups.

resultsTotal morphine consumption in the first 24 h was significantly higher in control than ESP and TPV groups (10.74 ± 1.37, 8.17 ± 1.69, 5.70 ± 1.95 respectively p < 0.001). Time to first analgesic request was the shortest in control versus ESP and TPV groups as (4.37 ± 3.06, 8.13 ± 1.75, 10.64 ± 1.83 h respectively p ˂0.001). ESP and TPV had significantly lower cortisol and prolactin levels compared to control (p < 0.001). The highest LANSS scores were in the control group in the first, third, and sixth months compared with ESP and TPV, with no significant difference between ESP and TPV.

conclusionESP and TPV blocks provided superior early postoperative analgesia and reduced stress response compared to the control group in female patients undergoing modified radical mastectomy. PVB is better than ESB in acute postoperative pain management (the total morphine consumption VAS score and time of first analgesic request). Both techniques showed better long-term outcomes compared to the control group regarding LANSS score in the 6-month follow-up.

trial registrationhttps://www. CLINICALTRIALS: gov trial registry (identifier NCT04498234 on 04/08/2020).

Indexed as

Chronic PainMastectomy, Modified RadicalNerve BlockPostoperative PainUltrasonography, InterventionalAcute PainAdultAnalgesics, OpioidAnesthetics, LocalBupivacaineFemaleHumansMiddle AgedMorphinePain MeasurementAnalgesics, OpioidAnesthetics, LocalBupivacaineMorphineErector spinae blockParavertebral blockPostmastectomy pain

Identifiers

PMID39574036
PMCPMC11580581

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.