ArticleNano letters2024
Thermophilic Behavior of Heat-Dissociative Coacervate Droplets.
Article in Nano letters, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Sustained formation movement and destruction of coacervates in a waste-free system driven by electricity.Nature communications · 2026Article
- Adaptive Coacervate Microreactors with Broad pH/Thermal Tolerance for Reaction Acceleration.JACS Au · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
In exploring the genesis of life, liquid-liquid phase-separated coacervate droplets have been proposed as primitive protocells. Within the hydrothermal hypothesis, these droplets would emerge from molecule-rich hot fluids and thus be subjected to temperature gradients. Investigating their thermophoretic behavior can provide insights into protocell footprints in thermal landscapes, advancing our understanding of life's origins. Here, we report the thermophilic behavior of heat-dissociative droplets, contrary to the intuition that heat-associative condensates would prefer hotter areas. This aspect implies the preferential presence of heat-dissociative primordial condensates near hydrothermal environments, facilitating molecular incorporation and biochemical syntheses. Additionally, our investigations reveal similarities between thermophoretic and electrophoretic motions, dictated by molecular redistribution within droplets due to their fluid nature, which necessitates revising current electrophoresis frameworks for surface charge characterization. Our study elucidates how coacervate droplets navigate thermal and electric fields, reveals their thermal-landscape-dependent molecular characteristics, and bridges foundational theories of early life: the hydrothermal and condensate-as-protocell hypotheses.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.