ArticleThe Journal of organic chemistry2024
Synthesis of Substituted Tetralins via Nitrogen Deletion/Diels-Alder Cascade Reaction.
Article in The Journal of organic chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Substituent-Controlled Ring Opening of 1-Substituted Benzocyclobutenes: Electronic Structure and Diradical Character of Ortho-Quinodimethane Intermediates.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- Generation of Mono- and BisazabicyclicOrganic letters · 2026Article
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Authors and funding
5 authors.
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Abstract
Skeletal editing is an important approach for the modification and diversification of biologically active molecules. The utilization of nitrogen deletion strategies in skeletal editing has recently emerged as a new method for compound modification. Here, we report an unexpected nitrogen deletion in isoindolines. Contrary to the anticipated outcome of cyclobutane formation via intramolecular radical couplings, the nitrogen deletion of isoindoline triggers a Diels-Alder cycloaddition facilitated by the in situ formation of
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Registered trials
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