Evidence map›Paper›PMID 39573829›Full record

ArticleThe American journal of case reports2024

Multidrug-Resistant Elizabethkingia meningoseptica and Enterococcus faecium Infection in an Oncohematologic Patient.

Cristina Motta Ferreira, Maria De Nazare Saunier Barbosa, Guilherme Motta Antunes Ferreira, Joseir Saturnino Cristino, Chesman Da Silva Alves, Erasmo Dos Santos Vieira, Larissa Alves Gomes, Vander Silva Souza, Franceline Oliveira Calheiros, William Antunes Ferreira

Abstract readCase Reports
In one paragraph

Article in The American journal of case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Pathogens (Basel, Switzerland) · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Cristina Motta FerreiraDepartment of Clinical Analysis, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Maria De Nazare Saunier BarbosaPatient Care Department, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Guilherme Motta Antunes FerreiraPostgraduate Program in Hematology, Amazonas State University - PPGH-UEA/HEMOAM, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Joseir Saturnino CristinoHospital Infection Control Commission-CCIH, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Chesman Da Silva AlvesPostgraduate Program in Hematology, Amazonas State University - PPGH-UEA/HEMOAM, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Erasmo Dos Santos VieiraPostgraduate Program in Hematology, Amazonas State University - PPGH-UEA/HEMOAM, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Larissa Alves GomesScientific Initiation Program-PAIC-FAPEAM/HEMOAM, Research Support Foundation of the State of Amazonas-FAPEAM, Manaus, AM, Brazil
Vander Silva SouzaDepartment of Clinical Analysis, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
Franceline Oliveira CalheirosDepartment of Clinical Analysis, Fundação Hospitalar de Hematologia e Hemoterapia do Amazonas, Manaus, AM, Brazil.
William Antunes FerreiraBacteriology Laboratory, Fundação de Dermatologia Tropical e Venereologia Alfredo da Matta-FUAM, Manaus, AM, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND This case report describes a case of a 25-year-old man who underwent a surgical procedure and was subsequently diagnosed with acute myeloid leukemia. Following his immediate admission to a specialized hospital unit for hematology and hemotherapy to receive chemotherapy, he was found to have a concurrent infection with multidrug-resistant Elizabethkingia meningoseptica as well as Enterococcus faecium. Both isolates are commonly associated with healthcare-associated infections. CASE REPORT The patient described in this report underwent an exploratory laparotomy, which is an invasive surgical procedure, and was subsequently diagnosed with acute myeloid leukemia following a biopsy. Chemotherapy was initiated immediately, during which the patient developed clinical signs and symptoms of infection. Blood cultures revealed the presence of Enterococcus faecium, while urine cultures identified Elizabethkingia meningoseptica. The VITEK-2 antibiogram for both bacteria revealed a multidrug resistance profile. E-test performed for glycopeptides indicated high-level resistance, with a minimum inhibitory concentration (MIC) exceeding 256 µg/mL. Prophylactic antibiotic therapy was initiated and subsequently adjusted according to the culture and antibiogram results. CONCLUSIONS Use of proper aseptic techniques during medical procedures is essential. Patients with severely compromised immunity undergoing numerous procedures require strict isolation measures to prevent infections, which can make the difference between life and death. Early laboratory identification of pathogenic clones and their antimicrobial resistance profiles is crucial for timely etiological diagnosis. This helps prevent the spread of infections and hospital infection outbreaks.

Indexed as

Drug Resistance, Multiple, BacterialEnterococcus faeciumFlavobacteriaceae InfectionsGram-Positive Bacterial InfectionsLeukemia, Myeloid, AcuteAdultAnti-Bacterial AgentsFlavobacteriaceaeHumansMaleAnti-Bacterial Agents

Identifiers

PMID39573829
PMCPMC11591303

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.