Pilot and feasibility studies in ophthalmology: fundamental keys to success.

Keean Nanji, Mark Phillips, Lehana Thabane, Yih Chung Tham, Tien Yin Wong, David H Steel, Marion R Munk, Charles C Wykoff, Varun Chaudhary, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group

Abstract readEditorial

PubMed Full text at PMC Publisher

In one paragraph

Article in Eye (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Keean NanjiMcMaster University, Department of Surgery, Division of Ophthalmology, Hamilton, ON, Canada.

Mark PhillipsMcMaster University, Department of Health Research Methods, Evidence and Impact, Hamilton, ON, Canada.ORCID http://orcid.org/0000-0003-0923-261X

Lehana ThabaneMcMaster University, Department of Health Research Methods, Evidence and Impact, Hamilton, ON, Canada.

Yih Chung ThamCentre for Innovation and Precision Eye Health; National University of Singapore, Singapore, Singapore.ORCID http://orcid.org/0000-0002-6752-797X

Tien Yin WongSingapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

David H SteelBioscience Institute, Newcastle University, Newcastle Upon Tyne, UK.ORCID http://orcid.org/0000-0001-8734-3089

Marion R MunkAugenarztpraxisgemeinschaft Gutblick AG, Pfäffikon, Switzerland.

Charles C WykoffRetina Consultants of Texas (Retina Consultants of America), Houston, TX, USA.

Varun ChaudharyMcMaster University, Department of Surgery, Division of Ophthalmology, Hamilton, ON, Canada. vchaudh@mcmaster.ca.ORCID http://orcid.org/0000-0002-9988-4146

Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39572846

DOI10.1038/s41433-024-03413-6

PMCPMC11733216

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.