Evidence map›Paper›PMID 39572686›Full record

ArticleNature human behaviour2025

The shared genetic architecture and evolution of human language and musical rhythm.

Gökberk Alagöz, Else Eising, Yasmina Mekki, Giacomo Bignardi, Pierre Fontanillas, 23andMe Research Team, Michel G Nivard, Michelle Luciano, Nancy J Cox, Simon E Fisher and 1 more

Abstract read
In one paragraph

Article in Nature human behaviour, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Distinct Rhythmic Competencies Identified via Internet-Based Assessment.Annals of the New York Academy of Sciences · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Gökberk AlagözLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands. goekberk.alagoez@mpi.nl.ORCID 0000-0003-0530-2780
Else EisingLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands.ORCID 0000-0001-9819-1260
Yasmina MekkiDepartment of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Giacomo BignardiLanguage and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands.ORCID 0000-0002-7439-0684
Pierre Fontanillas23andMe, Inc., Sunnyvale, CA, USA.ORCID 0000-0002-8944-4454
23andMe Research Team
Michel G NivardPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Michelle LucianoDepartment of Psychology, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-7306-3008
Nancy J CoxVanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Simon E Fisher *Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, the Netherlands. simon.fisher@mpi.nl.ORCID 0000-0002-3132-1996
Reyna L Gordon *Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. reyna.gordon@vanderbilt.edu.ORCID 0000-0003-1643-6979

Funding

Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
Neurobiological Markers of Rhythm: Risk and Resilience for Language AcquisitionR01DC016977 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2019 to 2023
$3.5M
Biomarkers of Rhythmic Communication: Integrating Foundational and Translational ApproachesDP2HD098859 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2018 to 2018
$2.4M
Mapping the Genetic and Neural Architecture of Human Rhythm and Communication TraitsK18DC017383 · NIDCD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GORDON, REYNA LEIGH · 2018 to 2019
$237k
NICHD NIH HHS DP2 HD098859NICHD NIH HHS P50 HD103537NIDCD NIH HHS K18 DC017383NIDCD NIH HHS R01 DC016977U.S. Department of Health & Human Services | NIH | National Institute on Deafness and Other Communication Disorders (NIDCD) R01DC016977
6 · The paper itself

Abstract

This study aimed to test theoretical predictions over biological underpinnings of previously documented phenotypic correlations between human language-related and musical rhythm traits. Here, after identifying significant genetic correlations between rhythm, dyslexia and various language-related traits, we adapted multivariate methods to capture genetic signals common to genome-wide association studies of rhythm (N = 606,825) and dyslexia (N = 1,138,870). The results revealed 16 pleiotropic loci (P < 5 × 10

Indexed as

Biological EvolutionDyslexiaLanguageMusicAdultBrainFemaleGenome-Wide Association StudyHumansMale

Identifiers

PMID39572686
PMCPMC11860242

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.