Evidence map›Paper›PMID 39572612›Full record

ArticleNature communications2024

Patterned electrical brain stimulation by a wireless network of implantable microdevices.

Ah-Hyoung Lee, Jihun Lee, Vincent Leung, Lawrence Larson, Arto Nurmikko

Erratum issuedAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Differential Tissue-Coupled Powering for Battery-Free Injectable Electroceuticals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Review
  4. Article
  5. Full-Stack Architectures for Intelligent Brain-Computer Interfaces.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  6. Article
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ah-Hyoung Lee *School of Engineering, Brown University, Providence, RI, USA.ORCID 0000-0003-1579-2816
Jihun Lee *School of Engineering, Brown University, Providence, RI, USA.ORCID 0000-0001-6251-3969
Vincent LeungElectrical and Computer Engineering, Baylor University, Waco, TX, USA.ORCID 0000-0002-1757-521X
Lawrence LarsonSchool of Engineering, Brown University, Providence, RI, USA.
Arto NurmikkoSchool of Engineering, Brown University, Providence, RI, USA. arto_nurmikko@brown.edu.ORCID 0000-0001-9668-2066

Funding

Brain Science Compute ClusterS10OD025181 · OD · BROWN UNIVERSITY · PI SANES, JEROME N · 2019 to 2019
$600k
National Science Foundation (NSF) 232600NIH HHS S10 OD025181
6 · The paper itself

Abstract

Transmitting meaningful information into brain circuits by electronic means is a challenge facing brain-computer interfaces. A key goal is to find an approach to inject spatially structured local current stimuli across swaths of sensory areas of the cortex. Here, we introduce a wireless approach to multipoint patterned electrical microstimulation by a spatially distributed epicortically implanted network of silicon microchips to target specific areas of the cortex. Each sub-millimeter-sized microchip harvests energy from an external radio-frequency source and converts this into biphasic current injected focally into tissue by a pair of integrated microwires. The amplitude, period, and repetition rate of injected current from each chip are controlled across the implant network by implementing a pre-scheduled, collision-free bitmap wireless communication protocol featuring sub-millisecond latency. As a proof-of-concept technology demonstration, a network of 30 wireless stimulators was chronically implanted into motor and sensory areas of the cortex in a freely moving rat for three months. We explored the effects of patterned intracortical electrical stimulation on trained animal behavior at average RF powers well below regulatory safety limits.

Indexed as

Brain-Computer InterfacesElectric StimulationWireless TechnologyAnimalsBehavior, AnimalBrainElectrodes, ImplantedMaleMotor CortexRats

Identifiers

PMID39572612
PMCPMC11582589

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.