Evidence map›Paper›PMID 39572492›Full record

ArticleBulletin of experimental biology and medicine2024

Transplantation of Cultured Mononuclear Fraction of Bone Marrow Cells in the Treatment of Heymann Nephritis in Rats.

L P Sigareva, A A Kokorina, E V Mikhailova, S V Kromsky, P A Slizhov, V N Aleksandrov, R A Nasyrov

Abstract read
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In one paragraph

Article in Bulletin of experimental biology and medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

L P SigarevaSt. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia. sigaryowa@yandex.ru.
A A KokorinaMinistry of Defense of the Russian Federation, S. M. Kirov Military Medical Academy, St. Petersburg, Russia.
E V MikhailovaSt. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
S V KromskySt. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
P A SlizhovMinistry of Defense of the Russian Federation, S. M. Kirov Military Medical Academy, St. Petersburg, Russia.
V N AleksandrovSt. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia.
R A NasyrovSt. Petersburg State Pediatric Medical University, Ministry of Health of the Russian Federation, St. Petersburg, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In an experiment on Wistar rats, a Heymann's active nephritis model was reproduced. After the chronic course of the disease was confirmed, we compared the effectiveness of single systemic and local transplantation of allogeneic cultured stromal cells of the mononuclear fraction of the bone marrow. Both methods of cell therapy reduced clinical manifestations of active Heymann's nephritis: proteinuria decreased and glomerular filtration rate increased 30 days after cell administration. At the histological level, signs of the inflammatory process manifested in an increase in the number of CD68

Indexed as

Bone Marrow TransplantationRats, WistarAnimalsAntigens, CDAntigens, Differentiation, MyelomonocyticBone Marrow CellsCD68 MoleculeCells, CulturedDisease Models, AnimalGlomerular Filtration RateGlomerulonephritisMaleProteinuriaRatsTransplantation, HomologousAntigens, CDAntigens, Differentiation, MyelomonocyticCD68 MoleculeCD68 protein, ratautoimmune glomerulonephritisbiomedical cell productCD68cell therapymesenchymal multipotent stromal cells

Identifiers

PMID39572492

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.