Evidence map›Paper›PMID 39572469›Full record

ArticleMolecular imaging and biology2025

The Potential Utility of (2S,4R)-4-[

Min-Jeong Kim, Hari K Akula, Jocelyn Marden, Kaixuan Li, Bao Hu, Paul Vaska, Wenchao Qu

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular imaging and biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Min-Jeong KimDepartment of Psychiatry and Behavioral Health, Stony Brook University School of Medicine, 101 Nicolls Rd, HSC T10-041L, Stony Brook, NY, 11794, USA. MinJeong.Kim@stonybrookmedicine.edu.ORCID http://orcid.org/0000-0002-0998-5972
Hari K AkulaDepartment of Psychiatry and Behavioral Health, Stony Brook University School of Medicine, 101 Nicolls Rd, HSC T10-041L, Stony Brook, NY, 11794, USA.
Jocelyn MardenDepartment of Psychiatry and Behavioral Health, Stony Brook University School of Medicine, 101 Nicolls Rd, HSC T10-041L, Stony Brook, NY, 11794, USA.
Kaixuan LiDepartment of Chemistry, Stony Brook University, Stony Brook, NY, USA.
Bao HuDepartment of Psychiatry and Behavioral Health, Stony Brook University School of Medicine, 101 Nicolls Rd, HSC T10-041L, Stony Brook, NY, 11794, USA.
Paul VaskaDepartment of Radiology, Stony Brook University School of Medicine, Stony Brook, NY, USA.
Wenchao QuDepartment of Psychiatry and Behavioral Health, Stony Brook University School of Medicine, 101 Nicolls Rd, HSC T10-041L, Stony Brook, NY, 11794, USA. Wenchao.Qu@stonybrook.edu.

Funding

Fluoride-Mediated Desilylative Radiosynthesis of 11C-Labeled PET TracersR01EB031785 · NIBIB · STATE UNIVERSITY NEW YORK STONY BROOK · PI QU, WENCHAO · 2022 to 2025
$1.4M
2020 Targeted Research Opportunity Program, Catacosinos Cancer Translational Researcher Award 2020 Targeted Research Opportunity Program, Catacosinos Cancer Translational Researcher AwardNIBIB NIH HHS R01EB031785
6 · The paper itself

Abstract

purpose(2S,4R)-4-[ PROCEDURES: The CIPE model (n = 4) was generated by injecting 200 µL of 3% carrageenan solution into the left hind paw three hours before the PET. The CIA model (n = 4) was generated by injecting 200 µg of collagen emulsion subcutaneously at the tail base 3-4 weeks before the PET. A qualitative scoring system was used to assess the severity of paw inflammation. After a CT scan, 15.7 ± 4.9 MBq of [

resultsThe CIPE models showed a trend toward higher uptake in the injected paw compared to the non-injected paw (P = 0.068). In CIA models, uptake in the paws with severe inflammation was significantly higher than the controls (P = 0.011), while that with mild and no inflammation was slightly higher (33%) and lower (-7%), respectively. Combined overall, the [

conclusions[

Indexed as

Arthritis, ExperimentalEdemaFluorine RadioisotopesGlutamineInflammationAnimalsBiomarkersCarrageenanDisease Models, AnimalMalePositron-Emission TomographyRatsBiomarkersCarrageenanFluorine RadioisotopesGlutamine(2S,4R)-4-[18F]FluoroglutamineGlutamineInflammationMetabolic imaging

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.