Evidence map›Paper›PMID 39572259›Full record

ReviewJournal of speech, language, and hearing research : JSLHR2025

Microbiome and Communication Disorders: A Tutorial for Clinicians.

Anumitha Venkatraman, Ruth Davis, Wen-Hsuan Tseng, Susan L Thibeault

Abstract readReview
In one paragraph

Review in Journal of speech, language, and hearing research : JSLHR, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anumitha VenkatramanDivision of Otolaryngology-Head & Neck Surgery, Department of Surgery, University of Wisconsin-Madison.
Ruth DavisDivision of Otolaryngology-Head & Neck Surgery, Department of Surgery, University of Wisconsin-Madison.
Wen-Hsuan TsengDivision of Otolaryngology-Head & Neck Surgery, Department of Surgery, University of Wisconsin-Madison.
Susan L ThibeaultDivision of Otolaryngology-Head & Neck Surgery, Department of Surgery, University of Wisconsin-Madison.ORCID 0000-0002-9046-4356

Funding

Engineering the Vocal Fold MucosaR01DC004336 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2000 to 2026
$14.6M
University of Wisconsin Voice Research Training Program (T32)T32DC009401 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2009 to 2026
$6.3M
Mechanisms of innate immune-microbial interactions in vocal fold InflammationR01DC012773 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI THIBEAULT, SUSAN LYNN · 2013 to 2022
$4.5M
Investigating the effects of psychosocial stress on laryngeal microbiology and epithelial barrier integrityF32DC021367 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI VENKATRAMAN, ANUMITHA · 2023 to 2024
$148k
NIDCD NIH HHS F32 DC021367NIDCD NIH HHS R01 DC004336NIDCD NIH HHS R01 DC012773NIDCD NIH HHS T32 DC009401
6 · The paper itself

Abstract

purposeEmerging research in the field of microbiology has indicated that host-microbiota interactions play a significant role in regulating health and disease. Whereas the gut microbiome has received the most attention, distinct microbiota in other organs (mouth, larynx, and trachea) may undergo microbial shifts that impact disease states. A comprehensive understanding of microbial mechanisms and their role in communication and swallowing deficits may have downstream diagnostic and therapeutic implications.

methodA literature review was completed to provide a broad overview of the microbiome, including differentiation of commensal versus pathogenic bacteria; cellular mechanisms by which bacteria interact with human cells; site-specific microbial compositional shifts in certain organs; and available reports of oral, laryngeal, and tracheal microbial dysbiosis in conditions that are associated with communication and swallowing deficits. RESULTS/

conclusionsThis review article is a valuable tutorial for clinicians, specifically introducing them to the concept of dysbiosis, with potential contributions to communication and swallowing deficits. Future research should delineate the role of specific pathogenic bacteria in disease pathogenesis to identify therapeutic targets.

Indexed as

Communication DisordersDysbiosisMicrobiotaDeglutition DisordersGastrointestinal MicrobiomeHumansMouth

Identifiers

PMID39572259
PMCPMC11842070

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.